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Human CLASP1 (aa 1-1538 )
CLASP1 Swiss - Prot #
Q7Z460
CLASP1 Protein names
CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1) (Multiple asters

homolog 1) (Protein Orbit homolog 1) (hOrbit1)
CLASP1 Gene names
CLASP1 KIAA0622 MAST1
Organism
Homo sapiens (Human)
CLASP1 Entry name
CLAP1_HUMAN

CLASP1 Codon-optimized cDNA Clone
CLASP1 CDNA Cat#
RPY2542
Tag
cDNA CLASP1 contains A 6x histidine tag
Condon optimized CLASP1 cDNA Formulation
Liquid
Condon optimized CLASP1 cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized CLASP1 cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant CLASP1 Protein
Recombinant CLASP1 Protein Cat#
PY2542
CLASP1 Protein Source
Recombinant protein
Recombinant CLASP1 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant CLASP1 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant CLASP1 Protein Activity
N/A
Tag
Recombinant CLASP1 contains A 6x histidine tag
Recombinant CLASP1 protein Formulation
Liquid
Recombinant CLASP1 protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant CLASP1Protein or cDNA
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CLASP1’s Protein family
CLASP family
CLASP1’s Subcellular locations
Cytoplasm > cytoskeleton. Cytoplasm > cytoskeleton > centrosome. Chromosome > centromere >

kinetochore. Cytoplasm > cytoskeleton > spindle. Golgi apparatus > trans-Golgi network.
CLASP1’s FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: Microtubule plus-end tracking protein that promotes the stabilization

of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules

originating from the trans-Golgi network (TGN). Required for the polarization of

the cytoplasmic microtubule arrays in migrating cells towards the leading edge of

the cell. May act at the cell cortex to enhance the frequency of rescue of

depolymerizing microtubules by attaching their plus-ends to cortical platforms

composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is

regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs

a similar stabilizing function at the kinetochore which is essential for the bipolar

alignment of chromosomes on the mitotic spindle.
CLASP1 Sequence databases
EMBL DDBJ GenBank
CLASP1 3D structure databases
ModBase
CLASP1’s Protein-protein interaction databases
STRING
CLASP1’s Proteomic databases
PRIDE
CLASP1’s Genome annotation databases
Ensembl GeneID KEGG UCSC
CLASP1’s Organism-specific databases
CTD MGI
CLASP1’s Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
CLASP1’s Gene expression databases
Bgee ArrayExpress Genevestigator
CLASP1’s Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.