| ARAP3 Swiss - Prot # |
| Q8WWN8 |
| ARAP3 Protein names |
| Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 |
| (Centaurin-delta-3) (Cnt-d3) |
| ARAP3 Gene names |
| ARAP3 CENTD3 |
| Organism |
| Homo sapiens (Human) |
| ARAP3 Entry name |
| ARAP3_HUMAN |
| ARAP3 Codon-optimized cDNA Clone |
| Tag |
| cDNA ARAP3 contains A 6x histidine tag |
| Condon optimized ARAP3 cDNA Formulation |
| Liquid |
| Condon optimized ARAP3 cDNA Storage |
| −20℃ to −70℃. Avoid repeated freeze-thaw cycles. |
| Condon optimized ARAP3 cDNA Application (s) |
| Applications: 1. Codon-optimized cDNA sequence designed for |
| recombinant protein production in both E.coli and Mammalian cell. The |
| cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2. |
| May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant ARAP3 Protein |
| Recombinant ARAP3 Protein Cat# |
| PY2545 |
| ARAP3 Protein Source |
| Recombinant protein |
| Recombinant ARAP3 Protein Applications |
| Western Blot, may be used for other applications determined by user |
| Recombinant ARAP3 Protein Purity |
| >90%, as determined by SDS-PAGE under reducing conditions |
| Recombinant ARAP3 Protein Activity |
| N/A |
| Tag |
| Recombinant ARAP3 contains A 6x histidine tag |
| Recombinant ARAP3 protein Formulation |
| Liquid |
| Recombinant ARAP3 protein Storage |
| −20℃ to −70℃. Avoid repeated freeze-thaw cycles. |
| ARAP3’s Subcellular locations |
| Cytoplasm. Cytoplasm > cytoskeleton. Cell membrane; Peripheral membrane protein. Cell projection > |
| lamellipodium. Cell projection > ruffle. |
| ARAP3’s FUNCTION (According to UniProtKB/Swiss-Prot) |
| FUNCTION: Phosphatidylinositol-3,4,5-trisphosphate-dependent GTPase- |
| activating protein that modulates actin cytoskeleton remodeling by regulating ARF |
| and RHO family members. Is activated by phosphatidylinositol-3,4,5-trisphosphate |
| (PtdIns(3,4,5)P3) binding. Can be activated by phosphatidylinositol-3,4- |
| bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency. Acts on ARF6, |
| RAC1, RHOA and CDC42. Plays a role in the internalization of anthrax toxin. |
| ARAP3 3D structure databases |
| ModBase |
| ARAP3’s Protein-protein interaction databases |
| STRING |
| ARAP3’s Proteomic databases |
| PRIDE |
| ARAP3’s Organism-specific databases |
| CTD |
MGI |
| FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS. |
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