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Mouse Rgnef (aa 1-1693 )
Rgnef Swiss - Prot #
P97433
Rgnef Protein names
Rho-guanine nucleotide exchange factor (190 kDa guanine nucleotide exchange factor)

(p190-RhoGEF) (p190RhoGEF) (Rho-interacting protein 2)
Rgnef Gene names
Rgnef Kiaa1998 Rhoip2 Rip2
Organism
Mus musculus (Mouse)
Rgnef Entry name
RGNEF_MOUSE

Rgnef Codon-optimized cDNA Clone
Rgnef CDNA Cat#
RPY2591
Tag
cDNA Rgnef contains A 6x histidine tag
Condon optimized Rgnef cDNA Formulation
Liquid
Condon optimized Rgnef cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized Rgnef cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant Rgnef Protein
Recombinant Rgnef Protein Cat#
PY2591
Rgnef Protein Source
Recombinant protein
Recombinant Rgnef Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Rgnef Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Rgnef Protein Activity
N/A
Tag
Recombinant Rgnef contains A 6x histidine tag
Recombinant Rgnef protein Formulation
Liquid
Recombinant Rgnef protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant RgnefProtein or cDNA
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Rgnef’s Protein family
Rgnef’s Subcellular locations
Cytoplasm. Cell membrane.
Rgnef’s FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: Functions as a RHOA-specific guanine nucleotide exchange factor

regulating signaling pathways downstream of integrins and growth factor

receptors. Functions in axonal branching, synapse formation and dendritic

morphogenesis. Functions also in focal adhesion formation, cell motility and B-

lymphocytes activation. May regulate NEFL expression and aggregation and play a

role in apoptosis.
Rgnef Sequence databases
EMBL DDBJ GenBank
Rgnef 3D structure databases
ModBase
Rgnef’s Protein-protein interaction databases
STRING
Rgnef’s Proteomic databases
PRIDE
Rgnef’s Genome annotation databases
Ensembl GeneID KEGG UCSC
Rgnef’s Organism-specific databases
CTD MGI
Rgnef’s Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
Rgnef’s Gene expression databases
Bgee ArrayExpress Genevestigator
Rgnef’s Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.