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Human RICTOR (aa 1-1708 )
RICTOR Swiss - Prot #
Q6R327
RICTOR Protein names
Rapamycin-insensitive companion of mTOR (AVO3 homolog) (hAVO3)
RICTOR Gene names
RICTOR KIAA1999
Organism
Homo sapiens (Human)
RICTOR Entry name
RICTR_HUMAN

RICTOR Codon-optimized cDNA Clone
RICTOR CDNA Cat#
RPY2598
Tag
cDNA RICTOR contains A 6x histidine tag
Condon optimized RICTOR cDNA Formulation
Liquid
Condon optimized RICTOR cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized RICTOR cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant RICTOR Protein
Recombinant RICTOR Protein Cat#
PY2598
RICTOR Protein Source
Recombinant protein
Recombinant RICTOR Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant RICTOR Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant RICTOR Protein Activity
N/A
Tag
Recombinant RICTOR contains A 6x histidine tag
Recombinant RICTOR protein Formulation
Liquid
Recombinant RICTOR protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant RICTORProtein or cDNA
For pricing and availability, Click Here >>>
RICTOR’s Protein family
Pianissimo family
RICTOR’s Subcellular locations
RICTOR’s FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: Subunit of mTORC2, which regulates cell growth and survival in

response to hormonal signals. mTORC2 is activated by growth factors, but, in

contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function

upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating

one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes

the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical

role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of

the activation loop of AKT1 on 'Thr-308' by PDK1 which is a prerequisite for full

activation. mTORC2 regulates the phosphorylation of SGK1 at 'Ser-422'. mTORC2

also modulates the phosphorylation of PRKCA on 'Ser-657'. Plays an essential role

in embryonic growth and development.
RICTOR Sequence databases
EMBL DDBJ GenBank
RICTOR 3D structure databases
ModBase
RICTOR’s Protein-protein interaction databases
STRING
RICTOR’s Proteomic databases
PRIDE
RICTOR’s Genome annotation databases
Ensembl GeneID KEGG UCSC
RICTOR’s Organism-specific databases
CTD MGI
RICTOR’s Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
RICTOR’s Gene expression databases
Bgee ArrayExpress Genevestigator
RICTOR’s Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.