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Human PLXNA1 (aa 1-1896 )
PLXNA1 Swiss - Prot #
Q9UIW2
PLXNA1 Protein names
Plexin-A1 (Semaphorin receptor NOV)
PLXNA1 Gene names
PLXNA1 NOV PLXN1
Organism
Homo sapiens (Human)
PLXNA1 Entry name
PLXA1_HUMAN

PLXNA1 Codon-optimized cDNA Clone
PLXNA1 CDNA Cat#
RPY2655
Tag
cDNA PLXNA1 contains A 6x histidine tag
Condon optimized PLXNA1 cDNA Formulation
Liquid
Condon optimized PLXNA1 cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized PLXNA1 cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant PLXNA1 Protein
Recombinant PLXNA1 Protein Cat#
PY2655
PLXNA1 Protein Source
Recombinant protein
Recombinant PLXNA1 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant PLXNA1 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant PLXNA1 Protein Activity
N/A
Tag
Recombinant PLXNA1 contains A 6x histidine tag
Recombinant PLXNA1 protein Formulation
Liquid
Recombinant PLXNA1 protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
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PLXNA1’s Protein family
Plexin family
PLXNA1’s Subcellular locations
Membrane; Single-pass type I membrane protein.
PLXNA1’s FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D.

Necessary for signaling by class 3 semaphorins and subsequent remodeling of the

cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.

Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The

plexin modulates the affinity of the complex for specific semaphorins, and its

cytoplasmic domain is required for the activation of down-stream signaling events

in the cytoplasm (By similarity).
PLXNA1 Sequence databases
EMBL DDBJ GenBank
PLXNA1 3D structure databases
ModBase
PLXNA1’s Protein-protein interaction databases
STRING
PLXNA1’s Proteomic databases
PRIDE
PLXNA1’s Genome annotation databases
Ensembl GeneID KEGG UCSC
PLXNA1’s Organism-specific databases
CTD MGI
PLXNA1’s Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
PLXNA1’s Gene expression databases
Bgee ArrayExpress Genevestigator
PLXNA1’s Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.