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Mouse Arhgap32 (aa 1-2089 )
Arhgap32 Swiss - Prot #
Q811P8
Arhgap32 Protein names
Rho GTPase-activating protein 32 (Brain-specific Rho GTPase-activating protein) (GAB-

associated Cdc42/Rac GTPase-activating protein) (GC-GAP) (Rho-type GTPase-activating

protein 32) (Rho/Cdc42/Rac GTPase-activating protein RICS) (RhoGAP involved in the

beta-catenin-N-cadherin and NMDA receptor signaling) (p200RhoGAP) (p250GAP)
Arhgap32 Gene names
Arhgap32 Grit Kiaa0712 Rics
Organism
Mus musculus (Mouse)
Arhgap32 Entry name
RHG32_MOUSE

Arhgap32 Codon-optimized cDNA Clone
Arhgap32 CDNA Cat#
RPY2695
Tag
cDNA Arhgap32 contains A 6x histidine tag
Condon optimized Arhgap32 cDNA Formulation
Liquid
Condon optimized Arhgap32 cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized Arhgap32 cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant Arhgap32 Protein
Recombinant Arhgap32 Protein Cat#
PY2695
Arhgap32 Protein Source
Recombinant protein
Recombinant Arhgap32 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Arhgap32 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Arhgap32 Protein Activity
N/A
Tag
Recombinant Arhgap32 contains A 6x histidine tag
Recombinant Arhgap32 protein Formulation
Liquid
Recombinant Arhgap32 protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
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Arhgap32’s Protein family
PX domain-containing GAP family
Arhgap32’s Subcellular locations
Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Cell projection >

dendritic spine. Cytoplasm > cell cortex. Endosome membrane. Golgi apparatus membrane.

Endoplasmic reticulum membrane. Membrane.
Arhgap32’s FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: GTPase-activating protein (GAP) promoting GTP hydrolysis on

RHOA, CDC42 and RAC1 small GTPases. May be involved in the differentiation of

neuronal cells during the formation of neurite extensions. Involved in NMDA

receptor activity-dependent actin reorganization in dendritic spines. May mediate

cross-talks between Ras- and Rho-regulated signaling pathways in cell growth

regulation. Isoform 2 has higher GAP activity.
Arhgap32 Sequence databases
EMBL DDBJ GenBank
Arhgap32 3D structure databases
ModBase
Arhgap32’s Protein-protein interaction databases
STRING
Arhgap32’s Proteomic databases
PRIDE
Arhgap32’s Genome annotation databases
Ensembl GeneID KEGG UCSC
Arhgap32’s Organism-specific databases
CTD MGI
Arhgap32’s Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
Arhgap32’s Gene expression databases
Bgee ArrayExpress Genevestigator
Arhgap32’s Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.