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Human DMBT1 (aa 1-2413 )
DMBT1 Swiss - Prot #
Q9UGM3
DMBT1 Protein names
Deleted in malignant brain tumors 1 protein (Glycoprotein 340) (Gp-340) (Hensin) (Salivary

agglutinin) (SAG) (Surfactant pulmonary-associated D-binding protein)
DMBT1 Gene names
DMBT1 GP340
Organism
Homo sapiens (Human)
DMBT1 Entry name
DMBT1_HUMAN

DMBT1 Codon-optimized cDNA Clone
DMBT1 CDNA Cat#
RPY2737
Tag
cDNA DMBT1 contains A 6x histidine tag
Condon optimized DMBT1 cDNA Formulation
Liquid
Condon optimized DMBT1 cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized DMBT1 cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant DMBT1 Protein
Recombinant DMBT1 Protein Cat#
PY2737
DMBT1 Protein Source
Recombinant protein
Recombinant DMBT1 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant DMBT1 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant DMBT1 Protein Activity
N/A
Tag
Recombinant DMBT1 contains A 6x histidine tag
Recombinant DMBT1 protein Formulation
Liquid
Recombinant DMBT1 protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant DMBT1Protein or cDNA
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DMBT1’s Protein family
DMBT1 family
DMBT1’s Subcellular locations
Secreted.
DMBT1’s FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: May be considered as a candidate tumor suppressor gene for brain,

lung, esophageal, gastric, and colorectal cancers. May play roles in mucosal

defense system, cellular immune defense and epithelial differentiation. May play a

role as an opsonin receptor for SFTPD and SPAR in macrophage tissues

throughout the body, including epithelial cells lining the gastrointestinal tract. May

play a role in liver regeneration. May be an important factor in fate decision and

differentiation of transit-amplifying ductular (oval) cells within the hepatic lineage.

Required for terminal differentiation of columnar epithelial cells during early

embryogenesis. May function as a binding protein in saliva for the regulation of

taste sensation. Binds to HIV-1 envelope protein and has been shown to both inhibit

and facilitate viral transmission. Displays a broad calcium-dependent binding

spectrum against both Gram-positive and Gram-negative bacteria, suggesting a

role in defense against bacterial pathogens. Binds to a range of poly-sulfated and

poly-phosphorylated ligands which may explain its broad bacterial-binding

specificity. Inhibits cytoinvasion of S.enterica. Associates with the actin cytoskeleton

and is involved in its remodeling during regulated exocytosis. Interacts with

pancreatic zymogens in a pH-dependent manner and may act as a Golgi cargo

receptor in the regulated secretory pathway of the pancreatic acinar cell.
DMBT1 Sequence databases
EMBL DDBJ GenBank
DMBT1 3D structure databases
ModBase
DMBT1’s Protein-protein interaction databases
STRING
DMBT1’s Proteomic databases
PRIDE
DMBT1’s Genome annotation databases
Ensembl GeneID KEGG UCSC
DMBT1’s Organism-specific databases
CTD MGI
DMBT1’s Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
DMBT1’s Gene expression databases
Bgee ArrayExpress Genevestigator
DMBT1’s Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.