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RAT Rhob (aa 1-196 )
Rhob Swiss-Prot #
P62747
Rhob Protein names
Rho-related GTP-binding protein RhoB
Rhob Gene names
Rhob Arhb
Organism
Rattus norvegicus (Rat)
Rhob Entry name
RHOB_RAT

Rhob Codon-optimized cDNA Clone
Rhob CDNA Cat#
RPY0274
Tag
cDNA Rhob contains A 6x histidine tag
Condon optimized Rhob cDNA Formulation
Liquid
Condon optimized Rhob cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized Rhob cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant Rhob Protein
Recombinant Rhob Protein Cat#
PY0274
Rhob Protein Source
Recombinant protein
Recombinant Rhob Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Rhob Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Rhob Protein Activity
N/A
Tag
Recombinant Rhob contains A 6x histidine tag
Condon optimized Rhob cDNA Formulation
Liquid
Condon optimized Rhob cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant Rhob Protein or cDNA
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Rhob Protein family
Small GTPase superfamily, Rho family
Rhob Subcellular locations
Late endosome membrane; Lipid-anchor. Cell membrane; Lipid-anchor. Nucleus.
Rhob FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: Mediates apoptosis in neoplastically transformed cells after DNA

damage. Not essential for development but affects cell adhesion and growth factor

signaling in transformed cells. Plays a negative role in tumorigenesis as deletion

causes tumor formation. Involved in intracellular protein trafficking of a number of

proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF

receptor from late endosomes to lysosomes. Also required for stability and nuclear

trafficking of AKT1/AKT which promotes endothelial cell survival during vascular

development (By similarity).
Rhob Sequence databases
EMBL DDBJ GenBank
Rhob 3D structure databases
ModBase
Rhob Protein-protein interaction databases
STRING
Rhob Proteomic databases
PRIDE
Rhob Genome annotation databases
Ensembl GeneID KEGG UCSC
Rhob Organism-specific databases
CTD MGI
Rhob Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
Rhob Gene expression databases
Bgee ArrayExpress Genevestigator
Rhob Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.