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Human FLNB (aa 1-2602 )
FLNB Swiss - Prot #
O75369
FLNB Protein names
Filamin-B (FLN-B) (ABP-278) (ABP-280 homolog) (Actin-binding-like protein) (Beta-filamin)

(Filamin homolog 1) (Fh1) (Filamin-3) (Thyroid autoantigen) (Truncated actin-binding

protein) (Truncated ABP)
FLNB Gene names
FLNB FLN1L FLN3 TABP TAP
Organism
Homo sapiens (Human)
FLNB Entry name
FLNB_HUMAN

FLNB Codon-optimized cDNA Clone
FLNB CDNA Cat#
RPY2766
Tag
cDNA FLNB contains A 6x histidine tag
Condon optimized FLNB cDNA Formulation
Liquid
Condon optimized FLNB cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized FLNB cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant FLNB Protein
Recombinant FLNB Protein Cat#
PY2766
FLNB Protein Source
Recombinant protein
Recombinant FLNB Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant FLNB Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant FLNB Protein Activity
N/A
Tag
Recombinant FLNB contains A 6x histidine tag
Recombinant FLNB protein Formulation
Liquid
Recombinant FLNB protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant FLNBProtein or cDNA
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FLNB’s Protein family
Filamin family
FLNB’s Subcellular locations
Cytoplasm > cell cortex. Cytoplasm > cytoskeleton. Cytoplasm > myofibril > sarcomere > Z-disk.

Cytoplasm > cytoskeleton.
FLNB’s FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: Connects cell membrane constituents to the actin cytoskeleton. May

promote orthogonal branching of actin filaments and links actin filaments to

membrane glycoproteins. Anchors various transmembrane proteins to the actin

cytoskeleton. Interaction with FLNA may allow neuroblast migration from the

ventricular zone into the cortical plate. Various interactions and localizations of

isoforms affect myotube morphology and myogenesis. Isoform 6 accelerates muscle

differentiation in vitro.
FLNB Sequence databases
EMBL DDBJ GenBank
FLNB 3D structure databases
ModBase
FLNB’s Protein-protein interaction databases
STRING
FLNB’s Proteomic databases
PRIDE
FLNB’s Genome annotation databases
Ensembl GeneID KEGG UCSC
FLNB’s Organism-specific databases
CTD MGI
FLNB’s Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
FLNB’s Gene expression databases
Bgee ArrayExpress Genevestigator
FLNB’s Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.