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RAT Hmgb1 (aa 1-215 )
Hmgb1 Swiss-Prot #
P63159
Hmgb1 Protein names
High mobility group protein B1 (Amphoterin) (Heparin-binding protein p30) (High mobility

group protein 1) (HMG-1)
Hmgb1 Gene names
Hmgb1 Hmg-1 Hmg1
Organism
Rattus norvegicus (Rat)
Hmgb1 Entry name
HMGB1_RAT

Hmgb1 Codon-optimized cDNA Clone
Hmgb1 CDNA Cat#
RPY0326
Tag
cDNA Hmgb1 contains A 6x histidine tag
Condon optimized Hmgb1 cDNA Formulation
Liquid
Condon optimized Hmgb1 cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized Hmgb1 cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant Hmgb1 Protein
Recombinant Hmgb1 Protein Cat#
PY0326
Hmgb1 Protein Source
Recombinant protein
Recombinant Hmgb1 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Hmgb1 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Hmgb1 Protein Activity
N/A
Tag
Recombinant Hmgb1 contains A 6x histidine tag
Recombinant Hmgb1 protein Formulation
Liquid
Recombinant Hmgb1 protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
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Hmgb1 Protein family
HMGB family
Hmgb1 Subcellular locations
Nucleus. Cytoplasm. Chromosome.
Hmgb1 FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: DNA binding proteins that associates with chromatin and has the

ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J

recombination by acting as a cofactor of the RAG complex. Acts by stimulating

cleavage and RAG protein binding at the 23 bp spacer of conserved recombination

signal sequences (RSS). Heparin-binding protein that has a role in the extension

of neurite-type cytoplasmic processes in developing cells (By similarity).
Hmgb1 Sequence databases
EMBL DDBJ GenBank
Hmgb1 3D structure databases
ModBase
Hmgb1 Protein-protein interaction databases
STRING
Hmgb1 Proteomic databases
PRIDE
Hmgb1 Genome annotation databases
Ensembl GeneID KEGG UCSC
Hmgb1 Organism-specific databases
CTD MGI
Hmgb1 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
Hmgb1 Gene expression databases
Bgee ArrayExpress Genevestigator
Hmgb1 Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.