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MOUSE Lin7a (aa 1-233 )
Lin7a Swiss-Prot #
Q8JZS0
Lin7a Protein names
Protein lin-7 homolog A (Lin-7A) (mLin-7) (Mammalian lin-seven protein 1) (MALS-1)

(Vertebrate lin-7 homolog 1) (Veli-1)
Lin7a Gene names
Lin7a Mals1 Veli1
Organism
Mus musculus (Mouse)
Lin7a Entry name
LIN7A_MOUSE

Lin7a Codon-optimized cDNA Clone
Lin7a CDNA Cat#
RPY0355
Tag
cDNA Lin7a contains A 6x histidine tag
Condon optimized Lin7a cDNA Formulation
Liquid
Condon optimized Lin7a cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized Lin7a cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag.

2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Lin7a Protein
Recombinant Lin7a Protein Cat#
PY0355
Lin7a Protein Source
Recombinant protein
Recombinant Lin7a Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Lin7a Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Lin7a Protein Activity
N/A
Tag
Recombinant Lin7a contains A 6x histidine tag
Recombinant Lin7a protein Formulation
Liquid
Recombinant Lin7a protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant Lin7a Protein or cDNA
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Lin7a Protein family
Lin-7 family
Lin7a Subcellular locations
Cell membrane; Peripheral membrane protein. Basolateral cell membrane; Peripheral membrane

protein. Cell junction. Cell junction > synapse > postsynaptic cell membrane > postsynaptic density;

Peripheral membrane protein. Cell junction > tight junction. Cell junction > synapse > synaptosome.
Lin7a FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: Plays a role in establishing and maintaining the asymmetric

distribution of channels and receptors at the plasma membrane of polarized cells.

Forms membrane-associated multiprotein complexes that may regulate delivery and

recycling of proteins to the correct membrane domains. The tripartite complex

composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the

potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the

proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal

postsynaptic density and may function in localizing synaptic vesicles at synapses

where it is recruited by beta-catenin and cadherin. Required to localize Kir2

channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and

ERBB4 to the basolateral membrane of epithelial cells.
Lin7a Sequence databases
EMBL DDBJ GenBank
Lin7a 3D structure databases
ModBase
Lin7a Protein-protein interaction databases
STRING
Lin7a Proteomic databases
PRIDE
Lin7a Genome annotation databases
Ensembl GeneID KEGG UCSC
Lin7a Organism-specific databases
CTD MGI
Lin7a Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
Lin7a Gene expression databases
Bgee ArrayExpress Genevestigator
Lin7a Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.