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HUMAN CLNS1A (aa 1-237 )
CLNS1A Swiss-Prot #
P54105
CLNS1A Protein names
Methylosome subunit pICln (Chloride channel, nucleotide sensitive 1A) (Chloride

conductance regulatory protein ICln) (I(Cln)) (Chloride ion current inducer protein) (ClCI)

(Reticulocyte pICln)
CLNS1A Gene names
CLNS1A CLCI ICLN
Organism
Homo sapiens (Human)
CLNS1A Entry name
ICLN_HUMAN

CLNS1A Codon-optimized cDNA Clone
CLNS1A CDNA Cat#
RPY0363
Tag
cDNA CLNS1A contains A 6x histidine tag
Condon optimized CLNS1A cDNA Formulation
Liquid
Condon optimized CLNS1A cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized CLNS1A cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag.

2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CLNS1A Protein
Recombinant CLNS1A Protein Cat#
PY0363
CLNS1A Protein Source
Recombinant protein
Recombinant CLNS1A Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant CLNS1A Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant CLNS1A Protein Activity
N/A
Tag
Recombinant CLNS1A contains A 6x histidine tag
Recombinant CLNS1A protein Formulation
Liquid
Recombinant CLNS1A protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
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CLNS1A Protein family
PICln family
CLNS1A Subcellular locations
Cytoplasm. Nucleus. Cytoplasm > cytoskeleton.
CLNS1A FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: The interaction with Sm proteins inhibits their assembly on U RNA

and interferes with snRNP biogenesis. Inhibits the binding of survival motor neuron

protein (SMN) to Sm proteins. May participate in cellular volume control by

activation of a swelling-induced chloride conductance pathway.
CLNS1A Sequence databases
EMBL DDBJ GenBank
CLNS1A 3D structure databases
ModBase
CLNS1A Protein-protein interaction databases
STRING
CLNS1A Proteomic databases
PRIDE
CLNS1A Genome annotation databases
Ensembl GeneID KEGG UCSC
CLNS1A Organism-specific databases
CTD MGI
CLNS1A Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
CLNS1A Gene expression databases
Bgee ArrayExpress Genevestigator
CLNS1A Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.