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HUMAN CDCA8 (aa 1-280 )
CDCA8 Swiss-Prot #
Q53HL2
CDCA8 Protein names
Borealin (Cell division cycle-associated protein 8) (Dasra-B) (hDasra-B) (Pluripotent

embryonic stem cell-related gene 3 protein)
CDCA8 Gene names
CDCA8 PESCRG3
Organism
Homo sapiens (Human)
CDCA8 Entry name
BOREA_HUMAN

CDCA8 Codon-optimized cDNA Clone
CDCA8 CDNA Cat#
RPY0460
Tag
cDNA CDCA8 contains A 6x histidine tag
Condon optimized CDCA8 cDNA Formulation
Liquid
Condon optimized CDCA8 cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized CDCA8 cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant CDCA8 Protein
Recombinant CDCA8 Protein Cat#
PY0460
CDCA8 Protein Source
Recombinant protein
Recombinant CDCA8 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant CDCA8 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant CDCA8 Protein Activity
N/A
Tag
Recombinant CDCA8 contains A 6x histidine tag
Recombinant CDCA8 protein Formulation
Liquid
Recombinant CDCA8 protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant CDCA8 Protein or cDNA
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CDCA8 Protein family
Borealin family
CDCA8 Subcellular locations
Nucleus > nucleolus. Cytoplasm. Cytoplasm > cytoskeleton > spindle. Chromosome > centromere.
CDCA8 FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: Component of the chromosomal passenger complex (CPC), a

complex that acts as a key regulator of mitosis. The CPC complex has essential

functions at the centromere in ensuring correct chromosome alignment and

segregation and is required for chromatin-induced microtubule stabilization and

spindle assembly. In the complex, it may be required to direct the CPC to

centromeric DNA. Major effector of the TTK kinase in the control of attachment-

error-correction and chromosome alignment.
CDCA8 Sequence databases
EMBL DDBJ GenBank
CDCA8 3D structure databases
ModBase
CDCA8 Protein-protein interaction databases
STRING
CDCA8 Proteomic databases
PRIDE
CDCA8 Genome annotation databases
Ensembl GeneID KEGG UCSC
CDCA8 Organism-specific databases
CTD MGI
CDCA8 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
CDCA8 Gene expression databases
Bgee ArrayExpress Genevestigator
CDCA8 Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.