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RAT Dynlt1 (aa 1-113 )
Dynlt1 Swiss-Prot #
Q9Z336
Dynlt1 Protein names
Dynein light chain Tctex-type 1 (Activator of G-protein signaling 2) (AGS2) (T-complex

testis-specific protein 1 homolog)
Dynlt1 Gene names
Dynlt1 Tctel1 Tctex-1 Tctex1
Organism
Rattus norvegicus (Rat)
Dynlt1 Entry name
DYLT1_RAT

Dynlt1 Codon-optimized cDNA Clone
Dynlt1 CDNA Cat#
RPY0048
Tag
cDNA Dynlt1 contains A 6x histidine tag
Condon optimized Dynlt1 cDNA Formulation
Liquid
Condon optimized Dynlt1 cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized Dynlt1 cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant Dynlt1 Protein
Recombinant Dynlt1 Protein Cat#
PY0048
Dynlt1 Protein Source
Recombinant protein
Recombinant Dynlt1 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Dynlt1 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Dynlt1 Protein Activity
N/A
Tag
Recombinant Dynlt1 contains A 6x histidine tag
Condon optimized Dynlt1 cDNA Formulation
Liquid
Condon optimized Dynlt1 cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant Dynlt1 Protein or cDNA
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Dynlt1 Protein family
Dynein light chain Tctex-type family
Dynlt1 Subcellular locations
Golgi apparatus. Cytoplasm. Cytoplasm > cytoskeleton > spindle.
Dynlt1 FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: Acts as one of several non-catalytic accessory components of the

cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to

cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1

acts as a motor for the intracellular retrograde motility of vesicles and organelles

along microtubules. Binds to transport cargos and is involved in apical cargo

transport such as rhodopsin-bearing vesicles in polarized epithelia. Is involved in

intracellular targeting of D-type retrovirus gag polyproteins to the cytoplasmic

assembly site. May also be a accessory component of axonemal dynein (By

similarity).; FUNCTION: Plays a role in neuronal morhpogenesis; the function is

independent of cytoplasmic dynein and seems to be coupled to regulation of the

actin cytoskeleton by enhancing Rac1 activity. Required for neurite outgrowth. The

function in neurogenesis may be regulated by association with a G-protein beta-

gamma dimer. May function as a receptor-independent activator of heterotrimeric

G-protein signaling; the activation appears to be independent of a nucleotide

exchange. Plays a role in regulating neurogenesis; inhibits the genesis of neurons

from precursor cells during cortical development presumably by antagonizing

ARHGEF2. Involved in the regulation of mitotic spindle orientation.
Dynlt1 Sequence databases
EMBL DDBJ GenBank
Dynlt1 3D structure databases
ModBase
Dynlt1 Protein-protein interaction databases
STRING
Dynlt1 Proteomic databases
PRIDE
Dynlt1 Genome annotation databases
Ensembl GeneID KEGG UCSC
Dynlt1 Organism-specific databases
CTD MGI
Dynlt1 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
Dynlt1 Gene expression databases
Bgee ArrayExpress Genevestigator
Dynlt1 Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.