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HUMAN CRK (aa 1-304 )
CRK Swiss-Prot #
P46108
CRK Protein names
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
CRK Gene names
CRK
Organism
Homo sapiens (Human)
CRK Entry name
CRK_HUMAN

CRK Codon-optimized cDNA Clone
CRK CDNA Cat#
RPY0545
Tag
cDNA CRK contains A 6x histidine tag
Condon optimized CRK cDNA Formulation
Liquid
Condon optimized CRK cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized CRK cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag.

2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CRK Protein
Recombinant CRK Protein Cat#
PY0545
CRK Protein Source
Recombinant protein
Recombinant CRK Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant CRK Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant CRK Protein Activity
N/A
Tag
Recombinant CRK contains A 6x histidine tag
Recombinant CRK protein Formulation
Liquid
Recombinant CRK protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant CRK Protein or cDNA
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CRK Protein family
CRK family
CRK Subcellular locations
Cytoplasm. Cell membrane.
CRK FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: The Crk-I and Crk-II forms differ in their biological activities. Crk-II

has less transforming activity than Crk-I. Crk-II mediates attachment-induced

MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner.

Involved in phagocytosis of apoptotic cells and cell motility via its interaction with

DOCK1 and DOCK4.
CRK Sequence databases
EMBL DDBJ GenBank
CRK 3D structure databases
ModBase
CRK Protein-protein interaction databases
STRING
CRK Proteomic databases
PRIDE
CRK Genome annotation databases
Ensembl GeneID KEGG UCSC
CRK Organism-specific databases
CTD MGI
CRK Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
CRK Gene expression databases
Bgee ArrayExpress Genevestigator
CRK Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.