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MOUSE Fcgr2 (aa 29-330 )
Fcgr2 Swiss-Prot #
P08101
Fcgr2 Protein names
Low affinity immunoglobulin gamma Fc region receptor II (Fc gamma receptor IIB) (Fc-

gamma RII) (Fc-gamma-RIIB) (FcRII) (IgG Fc receptor II beta) (Lymphocyte antigen 17) (Ly-

17) (CD antigen CD32)
Fcgr2 Gene names
Fcgr2 Fcgr2b Ly-17
Organism
Mus musculus (Mouse)
Fcgr2 Entry name
FCGR2_MOUSE

Fcgr2 Codon-optimized cDNA Clone
Fcgr2 CDNA Cat#
RPY0618
Tag
cDNA Fcgr2 contains A 6x histidine tag
Condon optimized Fcgr2 cDNA Formulation
Liquid
Condon optimized Fcgr2 cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized Fcgr2 cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant Fcgr2 Protein
Recombinant Fcgr2 Protein Cat#
PY0618
Fcgr2 Protein Source
Recombinant protein
Recombinant Fcgr2 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Fcgr2 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Fcgr2 Protein Activity
N/A
Tag
Recombinant Fcgr2 contains A 6x histidine tag
Recombinant Fcgr2 protein Formulation
Liquid
Recombinant Fcgr2 protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant Fcgr2 Protein or cDNA
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Fcgr2 Protein family
Fcgr2 Subcellular locations
Cell membrane; Single-pass type I membrane protein. Cytoplasm > cytoskeleton. Secreted.
Fcgr2 FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: Receptor for the Fc region of complexed immunoglobulins gamma.

Low affinity receptor. Involved in a variety of effector and regulatory functions such

as phagocytosis of antigen-antibody complexes from the circulation and modulation

of antibody production by B-cells. Isoform IIB1 and isoform IIB1' form caps but fail to

mediate endocytosis or phagocytosis. Isoform IIB2 can mediate the endocytosis of

soluble immune complexes via clathrin-coated pits. Isoform IIB1 and isoform IIB2

can down-regulate B-cell, T-cell, and mast cell activation when coaggregated to B-

cell receptors for AG (BCR), T-cell receptors for AG (TCR), and Fc receptors,

respectively.
Fcgr2 Sequence databases
EMBL DDBJ GenBank
Fcgr2 3D structure databases
ModBase
Fcgr2 Protein-protein interaction databases
STRING
Fcgr2 Proteomic databases
PRIDE
Fcgr2 Genome annotation databases
Ensembl GeneID KEGG UCSC
Fcgr2 Organism-specific databases
CTD MGI
Fcgr2 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
Fcgr2 Gene expression databases
Bgee ArrayExpress Genevestigator
Fcgr2 Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.