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MOUSE Angptl4 (aa 23-410 )
Angptl4 Swiss-Prot #
Q9Z1P8
Angptl4 Protein names
Angiopoietin-related protein 4 (425O18-1) (Angiopoietin-like protein 4) (Fasting-induced

adipose factor) (Hepatic fibrinogen/angiopoietin-related protein) (HFARP) (Secreted protein

Bk89)
Angptl4 Gene names
Angptl4 Farp Fiaf Ng27
Organism
Mus musculus (Mouse)
Angptl4 Entry name
ANGL4_MOUSE

Angptl4 Codon-optimized cDNA Clone
Angptl4 CDNA Cat#
RPY0878
Tag
cDNA Angptl4 contains A 6x histidine tag
Condon optimized Angptl4 cDNA Formulation
Liquid
Condon optimized Angptl4 cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized Angptl4 cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant Angptl4 Protein
Recombinant Angptl4 Protein Cat#
PY0878
Angptl4 Protein Source
Recombinant protein
Recombinant Angptl4 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Angptl4 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Angptl4 Protein Activity
N/A
Tag
Recombinant Angptl4 contains A 6x histidine tag
Recombinant Angptl4 protein Formulation
Liquid
Recombinant Angptl4 protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant Angptl4 Protein or cDNA
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Angptl4 Protein family
Angptl4 Subcellular locations
Secreted. Secreted > extracellular space > extracellular matrix.
Angptl4 FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: Protein with hypoxia-induced expression in endothelial cells. May act

as a regulator of angiogenesis and modulate tumorgenesis. Inhibits proliferation,

migration, and tubule formation of endothelial cells and reduces vascular leakage.

May exert a protective function on endothelial cells through an endocrine action. It is

directly involved in regulating glucose homeostasis, lipid metabolism, and insulin

sensitivity (By similarity). In response to hypoxia, the unprocessed form of the

protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-

associated and immobilized unprocessed form limits the formation of actin stress

fibers and focal contacts in the adhering endothelial cells and inhibits their

adhesion. It also decreases motility of endothelial cells and inhibits the sprouting

and tube formation.
Angptl4 Sequence databases
EMBL DDBJ GenBank
Angptl4 3D structure databases
ModBase
Angptl4 Protein-protein interaction databases
STRING
Angptl4 Proteomic databases
PRIDE
Angptl4 Genome annotation databases
Ensembl GeneID KEGG UCSC
Angptl4 Organism-specific databases
CTD MGI
Angptl4 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
Angptl4 Gene expression databases
Bgee ArrayExpress Genevestigator
Angptl4 Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.