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HUMAN PSTPIP1 (aa 1-416 )
PSTPIP1 Swiss-Prot #
O43586
PSTPIP1 Protein names
Proline-serine-threonine phosphatase-interacting protein 1 (PEST phosphatase-interacting

protein 1) (CD2-binding protein 1) (H-PIP)
PSTPIP1 Gene names
PSTPIP1 CD2BP1
Organism
Homo sapiens (Human)
PSTPIP1 Entry name
PPIP1_HUMAN

PSTPIP1 Codon-optimized cDNA Clone
PSTPIP1 CDNA Cat#
RPY0908
Tag
cDNA PSTPIP1 contains A 6x histidine tag
Condon optimized PSTPIP1 cDNA Formulation
Liquid
Condon optimized PSTPIP1 cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized PSTPIP1 cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant PSTPIP1 Protein
Recombinant PSTPIP1 Protein Cat#
PY0908
PSTPIP1 Protein Source
Recombinant protein
Recombinant PSTPIP1 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant PSTPIP1 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant PSTPIP1 Protein Activity
N/A
Tag
Recombinant PSTPIP1 contains A 6x histidine tag
Recombinant PSTPIP1 protein Formulation
Liquid
Recombinant PSTPIP1 protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant PSTPIP1 Protein or cDNA
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PSTPIP1 Protein family
PSTPIP1 Subcellular locations
Cytoplasm. Cytoplasm > cytoskeleton. Cell projection > lamellipodium. Cytoplasm > perinuclear

region. Cleavage furrow.
PSTPIP1 FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: Involved in regulation of the actin cytoskeleton. May regulate the WAS

actin-bundling activity. Bridges the interaction between ABL1 and PTPN18 leading

to the ABL1 dephosphorylation. May play a role as a scaffold protein between

PTPN12 and WAS and allows PTPN12 to dephosphorylate WAS. Has the potential

to physically couple CD2 and CD2AP to WAS. Acts downstream of CD2 and

CD2AP to recruit WAS to the T-cell:APC contact site so as to promote the actin

polymerization required for synapse induction during T-cell activation (By

similarity). Down-regulates CD2-stimulated adhesion through the coupling of

PTPN12 to CD2.
PSTPIP1 Sequence databases
EMBL DDBJ GenBank
PSTPIP1 3D structure databases
ModBase
PSTPIP1 Protein-protein interaction databases
STRING
PSTPIP1 Proteomic databases
PRIDE
PSTPIP1 Genome annotation databases
Ensembl GeneID KEGG UCSC
PSTPIP1 Organism-specific databases
CTD MGI
PSTPIP1 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
PSTPIP1 Gene expression databases
Bgee ArrayExpress Genevestigator
PSTPIP1 Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.