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MOUSE Terf1 (aa 1-421 )
Terf1 Swiss-Prot #
P70371
Terf1 Protein names
Telomeric repeat-binding factor 1 (TTAGGG repeat-binding factor 1)
Terf1 Gene names
Terf1 Trf1
Organism
Mus musculus (Mouse)
Terf1 Entry name
TERF1_MOUSE

Terf1 Codon-optimized cDNA Clone
Terf1 CDNA Cat#
RPY0940
Tag
cDNA Terf1 contains A 6x histidine tag
Condon optimized Terf1 cDNA Formulation
Liquid
Condon optimized Terf1 cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized Terf1 cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant Terf1 Protein
Recombinant Terf1 Protein Cat#
PY0940
Terf1 Protein Source
Recombinant protein
Recombinant Terf1 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Terf1 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Terf1 Protein Activity
N/A
Tag
Recombinant Terf1 contains A 6x histidine tag
Recombinant Terf1 protein Formulation
Liquid
Recombinant Terf1 protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant Terf1 Protein or cDNA
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Terf1 Protein family
Terf1 Subcellular locations
Nucleus. Chromosome > telomere. Cytoplasm > cytoskeleton > spindle.
Terf1 FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: Binds the telomeric double-stranded TTAGGG repeat and negatively

regulates telomere length. Involved in the regulation of the mitotic spindle.

Component of the shelterin complex (telosome) that is involved in the regulation of

telomere length and protection. Shelterin associates with arrays of double-stranded

TTAGGG repeats added by telomerase and protects chromosome ends; without its

protective activity, telomeres are no longer hidden from the DNA damage

surveillance and chromosome ends are inappropriately processed by DNA repair

pathways (By similarity).
Terf1 Sequence databases
EMBL DDBJ GenBank
Terf1 3D structure databases
ModBase
Terf1 Protein-protein interaction databases
STRING
Terf1 Proteomic databases
PRIDE
Terf1 Genome annotation databases
Ensembl GeneID KEGG UCSC
Terf1 Organism-specific databases
CTD MGI
Terf1 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
Terf1 Gene expression databases
Bgee ArrayExpress Genevestigator
Terf1 Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.