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MOUSE Ift57 (aa 1-429 )
Ift57 Swiss-Prot #
Q8BXG3
Ift57 Protein names
Intraflagellar transport protein 57 homolog (HIP1-interacting protein)
Ift57 Gene names
Ift57 Hippi
Organism
Mus musculus (Mouse)
Ift57 Entry name
IFT57_MOUSE

Ift57 Codon-optimized cDNA Clone
Ift57 CDNA Cat#
RPY0962
Tag
cDNA Ift57 contains A 6x histidine tag
Condon optimized Ift57 cDNA Formulation
Liquid
Condon optimized Ift57 cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized Ift57 cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant Ift57 Protein
Recombinant Ift57 Protein Cat#
PY0962
Ift57 Protein Source
Recombinant protein
Recombinant Ift57 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Ift57 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Ift57 Protein Activity
N/A
Tag
Recombinant Ift57 contains A 6x histidine tag
Recombinant Ift57 protein Formulation
Liquid
Recombinant Ift57 protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant Ift57 Protein or cDNA
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Ift57 Protein family
IFT57 family
Ift57 Subcellular locations
Cytoplasm > cytoskeleton > cilium basal body. Golgi apparatus.
Ift57 FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: Required for the formation of cilia. Plays an indirect role in sonic

hedgehog signaling, cilia being required for all activity of the hedgehog pathway.

Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-

8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-

AAAGACATG-3' present in the promoter of caspase genes such as CASP1,

CASP8 and CASP10, suggesting that it may act as a transcription regulator;

however the relevance of such function remains unclear.
Ift57 Sequence databases
EMBL DDBJ GenBank
Ift57 3D structure databases
ModBase
Ift57 Protein-protein interaction databases
STRING
Ift57 Proteomic databases
PRIDE
Ift57 Genome annotation databases
Ensembl GeneID KEGG UCSC
Ift57 Organism-specific databases
CTD MGI
Ift57 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
Ift57 Gene expression databases
Bgee ArrayExpress Genevestigator
Ift57 Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.