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MOUSE Pag1 (aa 24-429 )
Pag1 Swiss-Prot #
Q3U1F9
Pag1 Protein names
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (Csk-binding

protein) (Transmembrane phosphoprotein Cbp)
Pag1 Gene names
Pag1 Cbp Pag
Organism
Mus musculus (Mouse)
Pag1 Entry name
PAG1_MOUSE

Pag1 Codon-optimized cDNA Clone
Pag1 CDNA Cat#
RPY0963
Tag
cDNA Pag1 contains A 6x histidine tag
Condon optimized Pag1 cDNA Formulation
Liquid
Condon optimized Pag1 cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized Pag1 cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag.

2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Pag1 Protein
Recombinant Pag1 Protein Cat#
PY0963
Pag1 Protein Source
Recombinant protein
Recombinant Pag1 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Pag1 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Pag1 Protein Activity
N/A
Tag
Recombinant Pag1 contains A 6x histidine tag
Recombinant Pag1 protein Formulation
Liquid
Recombinant Pag1 protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant Pag1 Protein or cDNA
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Pag1 Protein family
Pag1 Subcellular locations
Cell membrane; Single-pass type III membrane protein.
Pag1 FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: Negatively regulates TCR (T-cell antigen receptor)-mediated

signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-

mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid

rafts, which results in LCK inhibition. Inhibits immunological synapse formation by

preventing dynamic arrangement of lipid raft proteins. May be involved in cell

adhesion signaling.
Pag1 Sequence databases
EMBL DDBJ GenBank
Pag1 3D structure databases
ModBase
Pag1 Protein-protein interaction databases
STRING
Pag1 Proteomic databases
PRIDE
Pag1 Genome annotation databases
Ensembl GeneID KEGG UCSC
Pag1 Organism-specific databases
CTD MGI
Pag1 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
Pag1 Gene expression databases
Bgee ArrayExpress Genevestigator
Pag1 Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.