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HUMAN DBNL (aa 1-430 )
DBNL Swiss-Prot #
Q9UJU6
DBNL Protein names
Drebrin-like protein (Cervical SH3P7) (Cervical mucin-associated protein) (Drebrin-F)

(HPK1-interacting protein of 55 kDa) (HIP-55) (SH3 domain-containing protein 7)
DBNL Gene names
DBNL CMAP SH3P7 PP5423
Organism
Homo sapiens (Human)
DBNL Entry name
DBNL_HUMAN

DBNL Codon-optimized cDNA Clone
DBNL CDNA Cat#
RPY0965
Tag
cDNA DBNL contains A 6x histidine tag
Condon optimized DBNL cDNA Formulation
Liquid
Condon optimized DBNL cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized DBNL cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag.

2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant DBNL Protein
Recombinant DBNL Protein Cat#
PY0965
DBNL Protein Source
Recombinant protein
Recombinant DBNL Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant DBNL Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant DBNL Protein Activity
N/A
Tag
Recombinant DBNL contains A 6x histidine tag
Recombinant DBNL protein Formulation
Liquid
Recombinant DBNL protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
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DBNL Protein family
ABP1 family
DBNL Subcellular locations
Cytoplasm > cytoskeleton. Cell projection > lamellipodium.
DBNL FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: Actin-binding adapter protein. May act as a common effector of

antigen receptor-signaling pathways in leukocytes. Its association with dynamin

suggests that it may also connect the actin cytoskeleton to endocytic function. Acts

as a key component of the immunological synapse that regulates T-cell activation by

bridging TCRs and the actin cytoskeleton to gene activation and endocytic

processes. Binds to F-actin but is not involved in actin polymerization, capping or

bundling. Does not bind G-actin.
DBNL Sequence databases
EMBL DDBJ GenBank
DBNL 3D structure databases
ModBase
DBNL Protein-protein interaction databases
STRING
DBNL Proteomic databases
PRIDE
DBNL Genome annotation databases
Ensembl GeneID KEGG UCSC
DBNL Organism-specific databases
CTD MGI
DBNL Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
DBNL Gene expression databases
Bgee ArrayExpress Genevestigator
DBNL Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.