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Human TRIB3 (aa 1-358)
TRIB3 Swiss Prot#
Q96RU7
TRIB3 Protein names
Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible putative kinase)

(p65-interacting inhibitor of NF-kappa-B) (SINK)
TRIB3 Gene names
TRIB3 (C20orf97) (NIPK) (SKIP3) (TRB3)
Organism
Human
TRIB3 Entry name
TRIB3_HUMAN
TRIB3 Codon optimized cDNA Clone
TRIB3 CDNA Cat#
RPC0180
cDNA Tag
cDNA TRIB3 Contains A 6x histidine tag
Condon optimized TRIB3 CDNA Formulation
Liquid
Condon optimized TRIB3 CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized TRIB3 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant TRIB3 Protein
Recombinant TRIB3 Protein Cat#
PC0180
TRIB3 Protein Source
Recombinant protein.
Recombinant TRIB3 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant TRIB3 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant TRIB3 Protein Activity
N/A
Recombinant protein Tag
Recombinant TRIB3 contains A 6x histidine tag
Recombinant TRIB3 Protein Formulation
Liquid
Recombinant TRIB3 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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TRIB3 Protein family
Protein kinase superfamily, CAMK Ser/Thr protein kinase family, Tribbles

subfamily
TRIB3 Subcellular locations
Nucleus.
TRIB3 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Disrupts insulin signaling by binding directly to Akt kinases and

blocking their activation. May bind directly to and mask the 'Thr-308'

phosphorylation site in AKT1. Binds to ATF4 and inhibits its transcriptional

activation activity. Interacts
TRIB3 Sequence databases
EMBL DDBJ GenBank
TRIB3 3D structure databases
ModBase
TRIB3 Protein-protein interaction databases
STRING
TRIB3 Proteomic databases
PRIDE
TRIB3 Genome annotation databases
Ensembl GeneID KEGG UCSC
TRIB3 Organism specific databases
CTD MGI
TRIB3 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
TRIB3 Gene expression databases
Bgee ArrayExpress Genevestigator
TRIB3 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY