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Magnetic Separator
Magnetic Beads and Applications
Affinity Magnetic Beads
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Ion Exchange Beads
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Antibody Purification & IP
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Antibody Immobilization
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Recombinant Protein
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Mouse Cables1 (aa 1-568)
Cables1 Swiss Prot#
Q9ESJ1
Cables1 Protein names
CDK5 and ABL1 enzyme substrate 1 (Interactor with CDK3 1) (Ik3-1)
Cables1 Gene names
Cables1 (Cables)
Organism
Mouse
Cables1 Entry name
CABL1_MOUSE
Cables1 Codon optimized cDNA Clone
Cables1 CDNA Cat#
RPI0218
cDNA Tag
cDNA Cables1 Contains A 6x histidine tag
Condon optimized Cables1 CDNA Formulation
Liquid
Condon optimized Cables1 CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized Cables1 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant Cables1 Protein
Recombinant Cables1 Protein Cat#
PI0218
Cables1 Protein Source
Recombinant protein.
Recombinant Cables1 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Cables1 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Cables1 Protein Activity
N/A
Recombinant protein Tag
Recombinant Cables1 contains A 6x histidine tag
Recombinant Cables1 Protein Formulation
Liquid
Recombinant Cables1 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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Cables1 Protein family
Cyclin family
Cables1 Subcellular locations
Nucleus. Cytoplasm. Cell projection > growth cone.
Cables1 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Cyclin-dependent kinase binding protein. Enhances cyclin-

dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases,

such as that of CDK5 by activated ABL1, which leads to increased CDK5

activity and is critical for neuronal development, and that of CDK2 by

WEE1, which leads to decreased CDK2 activity and growth inhibition.

Positively affects neuronal outgrowth. Plays a role as a regulator for

p53/p73-induced cell death (By similarity).
Cables1 Sequence databases
EMBL DDBJ GenBank
Cables1 3D structure databases
ModBase
Cables1 Protein-protein interaction databases
STRING
Cables1 Proteomic databases
PRIDE
Cables1 Genome annotation databases
Ensembl GeneID KEGG UCSC
Cables1 Organism specific databases
CTD MGI
Cables1 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
Cables1 Gene expression databases
Bgee ArrayExpress Genevestigator
Cables1 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY