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Human KLK6 (aa 17-244)
KLK6 Swiss Prot#
Q92876
KLK6 Protein names
Kallikrein-6 (EC 3.4.21.-) (Protease M) (Neurosin) (Zyme) (SP59) (Serine

protease 9) (Serine protease 18)
KLK6 Gene names
KLK6 (PRSS18) (PRSS9)
Organism
Human
KLK6 Entry name
KLK6_HUMAN
KLK6 Codon optimized cDNA Clone
KLK6 CDNA Cat#
RPI0083
cDNA Tag
cDNA KLK6 Contains A 6x histidine tag
Condon optimized KLK6 CDNA Formulation
Liquid
Condon optimized KLK6 CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized KLK6 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant KLK6 Protein

Recombinant KLK6 Protein Cat#
PI0083
KLK6 Protein Source
Recombinant protein.
Recombinant KLK6 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant KLK6 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant KLK6 Protein Activity
N/A
Recombinant protein Tag
Recombinant KLK6 contains A 6x histidine tag
Recombinant KLK6 Protein Formulation
Liquid
Recombinant KLK6 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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KLK6 Protein family
Peptidase S1 family, Kallikrein subfamily
KLK6 Subcellular locations
Secreted. Nucleus > nucleolus. Cytoplasm. Mitochondrion. Microsome.
KLK6 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Serine protease which exhibits a preference for Arg over Lys in

the substrate P1 position and for Ser or Pro in the P2 position. Shows

activity against amyloid precursor protein, myelin basic protein, gelatin,

casein and extracellular matrix proteins such as fibronectin, laminin,

vitronectin and collagen. Degrades alpha-synuclein and prevents its

polymerization, indicating that it may be involved in the pathogenesis of

Parkinson disease and other synucleinopathies. May be involved in

regulation of axon outgrowth following spinal cord injury. Tumor cells

treated with a neutralizing KLK6 antibody migrate less than control cells,

suggesting a role in invasion and metastasis.
KLK6 Sequence databases
EMBL DDBJ GenBank
KLK6 3D structure databases
ModBase
KLK6 Protein-protein interaction databases
STRING
KLK6 Proteomic databases
PRIDE
KLK6 Genome annotation databases
Ensembl GeneID KEGG UCSC
KLK6 Organism specific databases
CTD MGI
KLK6 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
KLK6 Gene expression databases
Bgee ArrayExpress Genevestigator
KLK6 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY