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Human Deformed epidermal autoregulatory factor 1 homolog (a.a.1-565)
DEAF1 Swiss Prot#
O75398
DEAF1 Protein names
Deformed epidermal autoregulatory factor 1 homolog (Nuclear DEAF-1-

related transcriptional regulator) (NUDR) (Suppressin) (Zinc finger MYND

domain-containing protein 5)
DEAF1 Gene names
DEAF1 SPN ZMYND5
Organism
Human
DEAF1 Entry name
DEAF1_HUMAN
DEAF1 Codon optimized cDNA Clone
DEAF1 CDNA Cat#
RPS0126
cDNA Tag
cDNA DEAF1 Contains A 6x histidine tag
Condon optimized DEAF1 CDNA Formulation
Liquid
Condon optimized DEAF1 CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized DEAF1 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant DEAF1 Protein
Recombinant DEAF1 Protein Cat#
PS0126
DEAF1 Protein Source
Recombinant protein.
Recombinant DEAF1 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant DEAF1 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant DEAF1 Protein Activity
N/A
Recombinant protein Tag
Recombinant DEAF1 contains A 6x histidine tag
Recombinant DEAF1 Protein Formulation
Liquid
Recombinant DEAF1 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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DEAF1 Protein family
-
DEAF1 Subcellular locations
Nucleus. Cytoplasm. Secreted. Cytoplasm. Nucleus.
DEAF1 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Transcription factor that binds to sequence with multiple copies

of 5'-TTC[CG]G-3' present in its own promoter and that of the HNRPA2B1

gene. Down-regulates transcription of these genes. Binds to the retinoic

acid response element (RARE) 5'-AGGGTTCACCGAAAGTTCA-3'. Activates

the proenkephalin gene independently of promoter binding, probably through

protein-protein interaction. When secreted, behaves as an inhibitor of cell

proliferation, by arresting cells in the G0 or G1 phase. Required for neural

tube closure and skeletal patterning. Regulates epithelial cell proliferation

and side-branching in the mammary gland. Controls the expression of

peripheral tissue antigens in pancreatic lymph nodes. Isoform 1 displays

greater transcriptional activity than isoform 4. Isoform 4 may inhibit

transcriptional activity of isoform 1 by interacting with isoform 1 and

retaining it in the cytoplasm.
DEAF1 Sequence databases
EMBL DDBJ GenBank
DEAF1 3D structure databases
ModBase
DEAF1 Protein-protein interaction databases
STRING
DEAF1 Proteomic databases
PRIDE
DEAF1 Genome annotation databases
Ensembl GeneID KEGG UCSC
DEAF1 Organism specific databases
CTD MGI
DEAF1 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
DEAF1 Gene expression databases
Bgee ArrayExpress Genevestigator
DEAF1 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY