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Human Cysteine protease ATG4B (a.a.1-393)
ATG4B Swiss Prot#
Q9Y4P1
ATG4B Protein names
Cysteine protease ATG4B (EC 3.4.22.-) (Autophagy-related protein 4 homolog

B) (hAPG4B) (Autophagin-1) (Autophagy-related cysteine endopeptidase 1)

(AUT-like 1 cysteine endopeptidase)
ATG4B Gene names
ATG4B APG4B AUTL1 KIAA0943
Organism
Human
ATG4B Entry name
ATG4B_HUMAN
ATG4B Codon optimized cDNA Clone
ATG4B CDNA Cat#
RPS0029
cDNA Tag
cDNA ATG4B Contains A 6x histidine tag
Condon optimized ATG4B CDNA Formulation
Liquid
Condon optimized ATG4B CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized ATG4B cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant ATG4B Protein
Recombinant ATG4B Protein Cat#
PS0029
ATG4B Protein Source
Recombinant protein.
Recombinant ATG4B Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant ATG4B Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant ATG4B Protein Activity
N/A
Recombinant protein Tag
Recombinant ATG4B contains A 6x histidine tag
Recombinant ATG4B Protein Formulation
Liquid
Recombinant ATG4B Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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ATG4B Protein family
Peptidase C54 family
ATG4B Subcellular locations
Cytoplasm.
ATG4B FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Cysteine protease required for autophagy, which cleaves the C-

terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the

liberation of form I. A subpopulation of form I is subsequently converted to a

smaller form (form II). Form II, with a revealed C-terminal glycine, is

considered to be the phosphatidylethanolamine (PE)-conjugated form, and

has the capacity for the binding to autophagosomes.
ATG4B Sequence databases
EMBL DDBJ GenBank
ATG4B 3D structure databases
ModBase
ATG4B Protein-protein interaction databases
STRING
ATG4B Proteomic databases
PRIDE
ATG4B Genome annotation databases
Ensembl GeneID KEGG UCSC
ATG4B Organism specific databases
CTD MGI
ATG4B Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
ATG4B Gene expression databases
Bgee ArrayExpress Genevestigator
ATG4B Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY