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Human Histone deacetylase 8 (a.a.1-377)
HDAC8 Swiss Prot#
Q9BY41
HDAC8 Protein names
Histone deacetylase 8 (HD8) (EC 3.5.1.98)
HDAC8 Gene names
HDAC8 HDACL1 CDA07
Organism
Human
HDAC8 Entry name
HDAC8_HUMAN
HDAC8 Codon optimized cDNA Clone
HDAC8 CDNA Cat#
RPS0293
cDNA Tag
cDNA HDAC8 Contains A 6x histidine tag
Condon optimized HDAC8 CDNA Formulation
Liquid
Condon optimized HDAC8 CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized HDAC8 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant HDAC8 Protein
Recombinant HDAC8 Protein Cat#
PS0293
HDAC8 Protein Source
Recombinant protein.
Recombinant HDAC8 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant HDAC8 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant HDAC8 Protein Activity
N/A
Recombinant protein Tag
Recombinant HDAC8 contains A 6x histidine tag
Recombinant HDAC8 Protein Formulation
Liquid
Recombinant HDAC8 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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HDAC8 Protein family
Histone deacetylase family, HD type 1 subfamily
HDAC8 Subcellular locations
Nucleus. Cytoplasm.
HDAC8 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Responsible for the deacetylation of lysine residues on the N-

terminal part of the core histones (H2A, H2B, H3 and H4). Histone

deacetylation gives a tag for epigenetic repression and plays an important

role in transcriptional regulation, cell cycle progression and developmental

events. Histone deacetylases act via the formation of large multiprotein

complexes. May play a role in smooth muscle cell contractility.
HDAC8 Sequence databases
EMBL DDBJ GenBank
HDAC8 3D structure databases
ModBase
HDAC8 Protein-protein interaction databases
STRING
HDAC8 Proteomic databases
PRIDE
HDAC8 Genome annotation databases
Ensembl GeneID KEGG UCSC
HDAC8 Organism specific databases
CTD MGI
HDAC8 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
HDAC8 Gene expression databases
Bgee ArrayExpress Genevestigator
HDAC8 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY