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Human DNA-binding protein Ikaros (a.a.1-519)

IKZF1 Swiss Prot#

Q13422

IKZF1 Protein names

DNA-binding protein Ikaros (Ikaros family zinc finger protein 1) (Lymphoid

transcription factor LyF-1)

IKZF1 Gene names

IKZF1 IK1 IKAROS LYF1 ZNFN1A1

Organism

Human

IKZF1 Entry name

IKZF1_HUMAN

IKZF1 Codon optimized cDNA Clone

IKZF1 CDNA Cat#

RPS0374

cDNA Tag

cDNA IKZF1 Contains A 6x histidine tag

Condon optimized IKZF1 CDNA Formulation

Liquid

Condon optimized IKZF1 CDNA Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

Condon optimized IKZF1 cDNA Applications

Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant IKZF1 Protein

Recombinant IKZF1 Protein Cat#

PS0374

IKZF1 Protein Source

Recombinant protein.

Recombinant IKZF1 Protein Applications

Western Blot, may be used for other applications determined by user

Recombinant IKZF1 Protein Purity

>90%, as determined by SDS-PAGE under reducing conditions

Recombinant IKZF1 Protein Activity

N/A

Recombinant protein Tag

Recombinant IKZF1 contains A 6x histidine tag

Recombinant IKZF1 Protein Formulation

Liquid

Recombinant IKZF1 Protein Storage

Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

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IKZF1 Protein family

Ikaros C2H2-type zinc-finger protein family

IKZF1 Subcellular locations

Nucleus. Cytoplasm.

IKZF1 FUNCTION (According to UniProtKB/Swiss Prot)

FUNCTION: Transcription regulator of hematopoietic cell differentiation.

Binds gamma-satellite DNA. Binds with higher affinity to gamma satellite A.

Plays a role in the development of lymphocytes, B- and T-cells. Binds and

activates the enhancer (delta-A element) of the CD3-delta gene. Repressor

of the TDT (terminal deoxynucleotidyltransferase) gene during thymocyte

differentiation. Regulates transcription through association with both HDAC-

dependent and HDAC-independent complexes. Targets the 2 chromatin-

remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex

(PYR complex), to the beta-globin locus in adult erythrocytes. Increases

normal apoptosis in adult erythroid cells. Confers early temporal

competence to retinal progenitor cells (RPCs) (By similarity).

IKZF1 Sequence databases

EMBL

DDBJ

GenBank

IKZF1 3D structure databases

ModBase

IKZF1 Protein-protein interaction databases

STRING

IKZF1 Proteomic databases

PRIDE

IKZF1 Genome annotation databases

Ensembl

GeneID

KEGG

UCSC

IKZF1 Organism specific databases

CTD

MGI

IKZF1 Phylogenomic databases

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

IKZF1 Gene expression databases

Bgee

ArrayExpress

Genevestigator

IKZF1 Family and domain databases

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY