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Human Class E basic helix-loop-helix protein 22 (a.a.1-381)
BHLHE22 Swiss Prot#
Q8NFJ8
BHLHE22 Protein names
Class E basic helix-loop-helix protein 22 (bHLHe22) (Class B basic helix-

loop-helix protein 5) (bHLHb5) (Trinucleotide repeat-containing gene 20

protein)
BHLHE22 Gene names
BHLHE22 BHLHB5 TNRC20
Organism
Human
BHLHE22 Entry name
BHE22_HUMAN
BHLHE22 Codon optimized cDNA Clone
BHLHE22 CDNA Cat#
RPS0040
cDNA Tag
cDNA BHLHE22 Contains A 6x histidine tag
Condon optimized BHLHE22 CDNA Formulation
Liquid
Condon optimized BHLHE22 CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized BHLHE22 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant BHLHE22 Protein
Recombinant BHLHE22 Protein Cat#
PS0040
BHLHE22 Protein Source
Recombinant protein.
Recombinant BHLHE22 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant BHLHE22 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant BHLHE22 Protein Activity
N/A
Recombinant protein Tag
Recombinant BHLHE22 contains A 6x histidine tag
Recombinant BHLHE22 Protein Formulation
Liquid
Recombinant BHLHE22 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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BHLHE22 Protein family
-
BHLHE22 Subcellular locations
Nucleus.
BHLHE22 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Inhibits DNA binding of TCF3/E47 homodimers and TCF3

(E47)/NEUROD1 heterodimers and acts as a strong repressor of Neurod1

and Myod-responsive genes, probably by heterodimerization with class a

basic helix-loop-helix factors. Despite the presence of an intact basic

domain, does not bind to DNA (By similarity).
BHLHE22 Sequence databases
EMBL DDBJ GenBank
BHLHE22 3D structure databases
ModBase
BHLHE22 Protein-protein interaction databases
STRING
BHLHE22 Proteomic databases
PRIDE
BHLHE22 Genome annotation databases
Ensembl GeneID KEGG UCSC
BHLHE22 Organism specific databases
CTD MGI
BHLHE22 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
BHLHE22 Gene expression databases
Bgee ArrayExpress Genevestigator
BHLHE22 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY