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Human Histone acetyltransferase KAT5 (a.a.1-513)
KAT5 Swiss Prot#
Q92993
KAT5 Protein names
Histone acetyltransferase KAT5 (EC 2.3.1.48) (Lysine acetyltransferase 5)

(Histone acetyltransferase HTATIP) (HIV-1 Tat interactive protein) (60 kDa

Tat-interactive protein) (Tip60) (cPLA(2)-interacting protein)
KAT5 Gene names
KAT5 HTATIP TIP60
Organism
Human
KAT5 Entry name
KAT5_HUMAN
KAT5 Codon optimized cDNA Clone
KAT5 CDNA Cat#
RPS0407
cDNA Tag
cDNA KAT5 Contains A 6x histidine tag
Condon optimized KAT5 CDNA Formulation
Liquid
Condon optimized KAT5 CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized KAT5 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant KAT5 Protein
Recombinant KAT5 Protein Cat#
PS0407
KAT5 Protein Source
Recombinant protein.
Recombinant KAT5 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant KAT5 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant KAT5 Protein Activity
N/A
Recombinant protein Tag
Recombinant KAT5 contains A 6x histidine tag
Recombinant KAT5 Protein Formulation
Liquid
Recombinant KAT5 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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KAT5 Protein family
MYST (SAS/MOZ) family
KAT5 Subcellular locations
Nucleus > nucleolus. Cytoplasm > perinuclear region.
KAT5 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Catalytic subunit of the NuA4 histone acetyltransferase complex

which is involved in transcriptional activation of select genes principally by

acetylation of nucleosomal histones H4 and H2A. This modification may both

alter nucleosome-DNA interactions and promote interaction of the modified

histones with other proteins which positively regulate transcription. This

complex may be required for the activation of transcriptional programs

associated with oncogene and proto-oncogene mediated growth induction,

tumor suppressor mediated growth arrest and replicative senescence,

apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair

when recruited to sites of DNA damage. Directly acetylates and activates

ATM. In case of HIV-1 infection, interaction with the viral Tat protein leads to

KAT5 polyubiquitination and targets it to degradation.
KAT5 Sequence databases
EMBL DDBJ GenBank
KAT5 3D structure databases
ModBase
KAT5 Protein-protein interaction databases
STRING
KAT5 Proteomic databases
PRIDE
KAT5 Genome annotation databases
Ensembl GeneID KEGG UCSC
KAT5 Organism specific databases
CTD MGI
KAT5 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
KAT5 Gene expression databases
Bgee ArrayExpress Genevestigator
KAT5 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY