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Human Transcriptional enhancer factor TEF-3 (a.a.1-434)

TEAD4 Swiss Prot#

Q15561

TEAD4 Protein names

Transcriptional enhancer factor TEF-3 (TEA domain family member 4) (TEAD-

4) (Transcription factor RTEF-1) (Transcription factor 13-like 1)

TEAD4 Gene names

TEAD4 RTEF1 TCF13L1 TEF3

Organism

Human

TEAD4 Entry name

TEAD4_HUMAN

TEAD4 Codon optimized cDNA Clone

TEAD4 CDNA Cat#

RPS0887

cDNA Tag

cDNA TEAD4 Contains A 6x histidine tag

Condon optimized TEAD4 CDNA Formulation

Liquid

Condon optimized TEAD4 CDNA Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

Condon optimized TEAD4 cDNA Applications

Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant TEAD4 Protein

Recombinant TEAD4 Protein Cat#

PS0887

TEAD4 Protein Source

Recombinant protein.

Recombinant TEAD4 Protein Applications

Western Blot, may be used for other applications determined by user

Recombinant TEAD4 Protein Purity

>90%, as determined by SDS-PAGE under reducing conditions

Recombinant TEAD4 Protein Activity

N/A

Recombinant protein Tag

Recombinant TEAD4 contains A 6x histidine tag

Recombinant TEAD4 Protein Formulation

Liquid

Recombinant TEAD4 Protein Storage

Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

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TEAD4 Protein family

TEAD4 Subcellular locations

Nucleus.

TEAD4 FUNCTION (According to UniProtKB/Swiss Prot)

FUNCTION: Transcription factor which plays a key role in the Hippo signaling

pathway, a pathway involved in organ size control and tumor suppression

by restricting proliferation and promoting apoptosis. The core of this pathway

is composed of a kinase cascade wherein MST1/MST2, in complex with its

regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex

with its regulatory protein MOB1, which in turn phosphorylates and

inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene

expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation,

migration and epithelial mesenchymal transition (EMT) induction. Binds

specifically and non-cooperatively to the Sph and GT-IIC 'enhansons' (5'-

GTGGAATGT-3') and activates transcription. Binds to the M-CAT motif.

TEAD4 Sequence databases

EMBL

DDBJ

GenBank

TEAD4 3D structure databases

ModBase

TEAD4 Protein-protein interaction databases

STRING

TEAD4 Proteomic databases

PRIDE

TEAD4 Genome annotation databases

Ensembl

GeneID

KEGG

UCSC

TEAD4 Organism specific databases

CTD

MGI

TEAD4 Phylogenomic databases

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

TEAD4 Gene expression databases

Bgee

ArrayExpress

Genevestigator

TEAD4 Family and domain databases

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY