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Human Phosphatidylinositol 3-kinase regulatory subunit alpha (a.a.113–301)
PIK3R1 Swiss Prot#
P27986
PIK3R1 Protein names
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85

subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K)
PIK3R1 Gene names
PIK3R1 (GRB1)
Organism
Human
PIK3R1 Entry name
P85A_HUMAN
PIK3R1 Codon optimized cDNA Clone
PIK3R1 CDNA Cat#
RPE0446
cDNA Tag
cDNA PIK3R1 Contains A 6x histidine tag
Condon optimized PIK3R1 CDNA Formulation
Liquid
Condon optimized PIK3R1 CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized PIK3R1 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant PIK3R1 Protein
Recombinant PIK3R1 Protein Cat#
PE0446
PIK3R1 Protein Source
Recombinant protein.
Recombinant PIK3R1 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant PIK3R1 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant PIK3R1 Protein Activity
N/A
Recombinant protein Tag
Recombinant PIK3R1 contains A 6x histidine tag
Recombinant PIK3R1 Protein Formulation
Liquid
Recombinant PIK3R1 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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PIK3R1 Protein family
PI3K p85 subunit family
PIK3R1 Subcellular locations
-
PIK3R1 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Binds to activated (phosphorylated) protein-Tyr kinases, through

its SH2 domain, and acts as an adapter, mediating the association of the

p110 catalytic unit to the plasma membrane. Necessary for the insulin-

stimulated increase in glucose uptake and glycogen synthesis in insulin-

sensitive tissues.
PIK3R1 Sequence databases
EMBL DDBJ GenBank
PIK3R1 3D structure databases
ModBase
PIK3R1 Protein-protein interaction databases
STRING
PIK3R1 Proteomic databases
PRIDE
PIK3R1 Genome annotation databases
Ensembl GeneID KEGG UCSC
PIK3R1 Organism specific databases
CTD MGI
PIK3R1 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
PIK3R1 Gene expression databases
Bgee ArrayExpress Genevestigator
PIK3R1 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY