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Human Bloom syndrome protein (a.a.676–851)

BLM Swiss Prot#

P54132

BLM Protein names

Bloom syndrome protein (EC 3.6.1.-) (RecQ protein-like 3) (DNA helicase,

RecQ-like type 2)

BLM Gene names

BLM (RECQ2) (RECQL3)

Organism

Human

BLM Entry name

BLM_HUMAN

BLM Codon optimized cDNA Clone

BLM CDNA Cat#

RPE0436

cDNA Tag

cDNA BLM Contains A 6x histidine tag

Condon optimized BLM CDNA Formulation

Liquid

Condon optimized BLM CDNA Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

Condon optimized BLM cDNA Applications

Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant BLM Protein

Recombinant BLM Protein Cat#

PE0436

BLM Protein Source

Recombinant protein.

Recombinant BLM Protein Applications

Western Blot, may be used for other applications determined by user

Recombinant BLM Protein Purity

>90%, as determined by SDS-PAGE under reducing conditions

Recombinant BLM Protein Activity

N/A

Recombinant protein Tag

Recombinant BLM contains A 6x histidine tag

Recombinant BLM Protein Formulation

Liquid

Recombinant BLM Protein Storage

Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

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BLM Protein family

Helicase family, RecQ subfamily

BLM Subcellular locations

Nucleus.

BLM FUNCTION (According to UniProtKB/Swiss Prot)

FUNCTION: Participates in DNA replication and repair. Exhibits a

magnesium-dependent ATP-dependent DNA-helicase activity that unwinds

single- and double-stranded DNA in a 3'-5' direction.

BLM Sequence databases

EMBL

DDBJ

GenBank

BLM 3D structure databases

ModBase

BLM Protein-protein interaction databases

STRING

BLM Proteomic databases

PRIDE

BLM Genome annotation databases

Ensembl

GeneID

KEGG

UCSC

BLM Organism specific databases

CTD

MGI

BLM Phylogenomic databases

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

BLM Gene expression databases

Bgee

ArrayExpress

Genevestigator

BLM Family and domain databases

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY