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Human Angiotensin-converting enzyme (a.a.30-350)
ACE Swiss Prot#
P12821
ACE Protein names
Angiotensin-converting enzyme (ACE) (EC 3.4.15.1) (EC 3.2.1.-) (Dipeptidyl

carboxypeptidase I) (Kininase II) (CD antigen CD143) [Cleaved into:

Angiotensin-converting enzyme, soluble form]
ACE Gene names
ACE (DCP) (DCP1)
Organism
Human
ACE Entry name
Sideroflexin-4 (Breast cancer resistance marker 1)
ACE Codon optimized cDNA Clone
ACE CDNA Cat#
RPE0591
cDNA Tag
cDNA ACE Contains A 6x histidine tag
Condon optimized ACE CDNA Formulation
Liquid
Condon optimized ACE CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized ACE cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant ACE Protein
Recombinant ACE Protein Cat#
PE0591
ACE Protein Source
Recombinant protein.
Recombinant ACE Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant ACE Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant ACE Protein Activity
N/A
Recombinant protein Tag
Recombinant ACE contains A 6x histidine tag
Recombinant ACE Protein Formulation
Liquid
Recombinant ACE Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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ACE Protein family
Peptidase M2 family
ACE Subcellular locations
Secreted. Cell membrane; Single-pass type I membrane protein.
ACE FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Converts angiotensin I to angiotensin II by release of the

terminal His-Leu, this results in an increase of the vasoconstrictor activity

of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has

also a glycosidase activity which releases GPI-anchored proteins from the

membrane by cleaving the mannose linkage in the GPI moiety.
ACE Sequence databases
EMBL DDBJ GenBank
ACE 3D structure databases
ModBase
ACE Protein-protein interaction databases
STRING
ACE Proteomic databases
PRIDE
ACE Genome annotation databases
Ensembl GeneID KEGG UCSC
ACE Organism specific databases
CTD MGI
ACE Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
ACE Gene expression databases
Bgee ArrayExpress Genevestigator
ACE Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY