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Human CD59 glycoprotein (a.a.26–102)

CD59 Swiss Prot#

P13987

CD59 Protein names

CD59 glycoprotein (Membrane attack complex inhibition factor) (MACIF)

(MAC-inhibitory protein) (MAC-IP) (Protectin) (MEM43 antigen) (Membrane

inhibitor of reactive lysis) (MIRL) (20 kDa homologous restriction factor)

(HRF-20) (HRF20) (1F5 antigen) (CD ant

CD59 Gene names

CD59 (MIC11) (MIN1) (MIN2) (MIN3) (MSK21)

Organism

Human

CD59 Entry name

CD59_HUMAN

CD59 Codon optimized cDNA Clone

CD59 CDNA Cat#

RPE0417

cDNA Tag

cDNA CD59 Contains A 6x histidine tag

Condon optimized CD59 CDNA Formulation

Liquid

Condon optimized CD59 CDNA Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

Condon optimized CD59 cDNA Applications

Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant CD59 Protein

Recombinant CD59 Protein Cat#

PE0417

CD59 Protein Source

Recombinant protein.

Recombinant CD59 Protein Applications

Western Blot, may be used for other applications determined by user

Recombinant CD59 Protein Purity

>90%, as determined by SDS-PAGE under reducing conditions

Recombinant CD59 Protein Activity

N/A

Recombinant protein Tag

Recombinant CD59 contains A 6x histidine tag

Recombinant CD59 Protein Formulation

Liquid

Recombinant CD59 Protein Storage

Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

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CD59 Protein family

CD59 Subcellular locations

Cell membrane; Lipid-anchor > GPI-anchor. Secreted.

CD59 FUNCTION (According to UniProtKB/Swiss Prot)

FUNCTION: Potent inhibitor of the complement membrane attack complex

(MAC) action. Acts by binding to the C8 and/or C9 complements of the

assembling MAC, thereby preventing incorporation of the multiple copies of

C9 required for complete formation of the osmolytic pore. This inhibitor

appears to be species-specific. Involved in signal transduction for T-cell

activation complexed to a protein tyrosine kinase.; FUNCTION: The soluble

form from urine retains its specific complement binding activity, but exhibits

greatly reduced ability to inhibit MAC assembly on cell membranes.

CD59 Sequence databases

EMBL

DDBJ

GenBank

CD59 3D structure databases

ModBase

CD59 Protein-protein interaction databases

STRING

CD59 Proteomic databases

PRIDE

CD59 Genome annotation databases

Ensembl

GeneID

KEGG

UCSC

CD59 Organism specific databases

CTD

MGI

CD59 Phylogenomic databases

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CD59 Gene expression databases

Bgee

ArrayExpress

Genevestigator

CD59 Family and domain databases

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY