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Affinity Magnetic Beads
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Human CSPG4 (a.a.202–380)
CSPG4 Swiss Prot#
Q6UVK1
CSPG4 Protein names
CSPG4 (MCSP)
CSPG4 Gene names
CSPG4
Organism
Human
CSPG4 Entry name
Chondroitin sulfate proteoglycan 4 (Chondroitin sulfate proteoglycan NG2) (Melanoma

chondroitin sulfate proteoglycan) (Melanoma-associated chondroitin sulfate

proteoglycan)
CSPG4 Codon optimized cDNA Clone
CSPG4 CDNA Cat#
RPE0440
cDNA Tag
cDNA CSPG4 Contains A 6x histidine tag
Condon optimized CSPG4 CDNA Formulation
Liquid
Condon optimized CSPG4 CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized CSPG4 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant CSPG4 Protein
Recombinant CSPG4 Protein Cat#
PE0440
CSPG4 Protein Source
Recombinant protein.
Recombinant CSPG4 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant CSPG4 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant CSPG4 Protein Activity
N/A
Recombinant protein Tag
Recombinant CSPG4 contains A 6x histidine tag
Recombinant CSPG4 Protein Formulation
Liquid
Recombinant CSPG4 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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CSPG4 Protein family
-
CSPG4 Subcellular locations
Apical cell membrane; Single-pass type I membrane protein; Extracellular

side. Cell projection > lamellipodium membrane; Single-pass type I

membrane protein; Extracellular side.
CSPG4 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Proteoglycan playing a role in cell proliferation and migration

which stimulates endothelial cells motility during microvascular

morphogenesis. May also inhibit neurite outgrowth and growth cone collapse

during axon regeneration. Cell surface receptor for collagen alpha 2(VI)

which may confer cells ability to migrate on that substrate. Binds through its

extracellular N-terminus growth factors, extracellular matrix proteases

modulating their activity. May regulate MPP16-dependent degradation and

invasion of type I collagen participating in melanoma cells invasion

properties. May modulate the plasminogen system by enhancing

plasminogen activation and inhibiting angiostatin. Functions also as a

signal transducing protein by binding through its cytoplasmic C-terminus

scaffolding and signaling proteins. May promote retraction fiber formation

and cell polarization through Rho GTPase activation. May stimulate alpha-4,

beta-1 integrin-mediated adhesion and spreading by recruiting and

activating a signaling cascade through CDC42, ACK1 and BCAR1. May

activate FAK and ERK1/ERK2 signaling cascades.
CSPG4 Sequence databases
EMBL DDBJ GenBank
CSPG4 3D structure databases
ModBase
CSPG4 Protein-protein interaction databases
STRING
CSPG4 Proteomic databases
PRIDE
CSPG4 Genome annotation databases
Ensembl GeneID KEGG UCSC
CSPG4 Organism specific databases
CTD MGI
CSPG4 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
CSPG4 Gene expression databases
Bgee ArrayExpress Genevestigator
CSPG4 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY