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Human Nuclear factor NF-kappa-B p100 subunit (a.a.1–454)

NFKB2 Swiss Prot#

Q00653

NFKB2 Protein names

Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1)

(Lymphocyte translocation chromosome 10) (Oncogene Lyt-10) (Lyt10)

[Cleaved into: Nuclear factor NF-kappa-B p52 subunit]

NFKB2 Gene names

NFKB2 (LYT10)

Organism

Human

NFKB2 Entry name

RUNX1_HUMAN

NFKB2 Codon optimized cDNA Clone

NFKB2 CDNA Cat#

RPE0733

cDNA Tag

cDNA NFKB2 Contains A 6x histidine tag

Condon optimized NFKB2 CDNA Formulation

Liquid

Condon optimized NFKB2 CDNA Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

Condon optimized NFKB2 cDNA Applications

Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant NFKB2 Protein

Recombinant NFKB2 Protein Cat#

PE0733

NFKB2 Protein Source

Recombinant protein.

Recombinant NFKB2 Protein Applications

Western Blot, may be used for other applications determined by user

Recombinant NFKB2 Protein Purity

>90%, as determined by SDS-PAGE under reducing conditions

Recombinant NFKB2 Protein Activity

N/A

Recombinant protein Tag

Recombinant NFKB2 contains A 6x histidine tag

Recombinant NFKB2 Protein Formulation

Liquid

Recombinant NFKB2 Protein Storage

Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

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NFKB2 Protein family

NFKB2 Subcellular locations

Nucleus. Cytoplasm.

NFKB2 FUNCTION (According to UniProtKB/Swiss Prot)

FUNCTION: NF-kappa-B is a pleiotropic transcription factor which is present

in almost all cell types and is involved in many biological processed such

as inflammation, immunity, differentiation, cell growth, tumorigenesis and

apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the

Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105,

NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the

DNA of their target genes and the individual dimers have distinct

preferences for different kappa-B sites that they can bind with

distinguishable affinity and specificity. Different dimer combinations act as

transcriptional activators or repressors, respectively. NF-kappa-B is

controlled by various mechanisms of post-translational modification and

subcellular compartmentalization as well as by interactions with other

cofactors or corepressors.

NFKB2 Sequence databases

EMBL

DDBJ

GenBank

NFKB2 3D structure databases

ModBase

NFKB2 Protein-protein interaction databases

STRING

NFKB2 Proteomic databases

PRIDE

NFKB2 Genome annotation databases

Ensembl

GeneID

KEGG

UCSC

NFKB2 Organism specific databases

CTD

MGI

NFKB2 Phylogenomic databases

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

NFKB2 Gene expression databases

Bgee

ArrayExpress

Genevestigator

NFKB2 Family and domain databases

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY