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Magnetic Separator
Magnetic Beads and Applications
Affinity Magnetic Beads
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Antibody Purification & IP
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Recombinant Protein
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Human PIAS1 (a.a.124–288)
PIAS1 Swiss Prot#
O75925
PIAS1 Protein names
PIAS1 (DDXBP1)
PIAS1 Gene names
PIAS1
Organism
Human
PIAS1 Entry name
Plakophilin-2
PIAS1 Codon optimized cDNA Clone
PIAS1 CDNA Cat#
RPE0429
cDNA Tag
cDNA PIAS1 Contains A 6x histidine tag
Condon optimized PIAS1 CDNA Formulation
Liquid
Condon optimized PIAS1 CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized PIAS1 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant PIAS1 Protein
Recombinant PIAS1 Protein Cat#
PE0429
PIAS1 Protein Source
Recombinant protein.
Recombinant PIAS1 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant PIAS1 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant PIAS1 Protein Activity
N/A
Recombinant protein Tag
Recombinant PIAS1 contains A 6x histidine tag
Recombinant PIAS1 Protein Formulation
Liquid
Recombinant PIAS1 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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PIAS1 Protein family
PIAS family
PIAS1 Subcellular locations
Nucleus speckle.
PIAS1 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Functions as an E3-type small ubiquitin-like modifier (SUMO)

ligase, stabilizing the interaction between UBE2I and the substrate, and as a

SUMO-tethering factor. Plays a crucial role as a transcriptional

coregulation in various cellular pathways, including the STAT pathway, the

p53 pathway and the steroid hormone signaling pathway. In vitro, binds A/T-

rich DNA. The effects of this transcriptional coregulation, transactivation or

silencing, may vary depending upon the biological context. Together with

PRMT1, may repress STAT1 transcriptional activity, in the late phase of

interferon gamma (IFN-gamma) signaling.
PIAS1 Sequence databases
EMBL DDBJ GenBank
PIAS1 3D structure databases
ModBase
PIAS1 Protein-protein interaction databases
STRING
PIAS1 Proteomic databases
PRIDE
PIAS1 Genome annotation databases
Ensembl GeneID KEGG UCSC
PIAS1 Organism specific databases
CTD MGI
PIAS1 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
PIAS1 Gene expression databases
Bgee ArrayExpress Genevestigator
PIAS1 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY