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Human Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (a.a.1–163)

PIN1 Swiss Prot#

Q13526

PIN1 Protein names

Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (EC 5.2.1.8)

(Rotamase Pin1) (PPIase Pin1)

PIN1 Gene names

PIN1

Organism

Human

PIN1 Entry name

PIN1_HUMAN

PIN1 Codon optimized cDNA Clone

PIN1 CDNA Cat#

RPE0426

cDNA Tag

cDNA PIN1 Contains A 6x histidine tag

Condon optimized PIN1 CDNA Formulation

Liquid

Condon optimized PIN1 CDNA Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

Condon optimized PIN1 cDNA Applications

Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant PIN1 Protein

Recombinant PIN1 Protein Cat#

PE0426

PIN1 Protein Source

Recombinant protein.

Recombinant PIN1 Protein Applications

Western Blot, may be used for other applications determined by user

Recombinant PIN1 Protein Purity

>90%, as determined by SDS-PAGE under reducing conditions

Recombinant PIN1 Protein Activity

N/A

Recombinant protein Tag

Recombinant PIN1 contains A 6x histidine tag

Recombinant PIN1 Protein Formulation

Liquid

Recombinant PIN1 Protein Storage

Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

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PIN1 Protein family

PIN1 Subcellular locations

Nucleus.

PIN1 FUNCTION (According to UniProtKB/Swiss Prot)

FUNCTION: Essential PPIase that regulates mitosis presumably by

interacting with NIMA and attenuating its mitosis-promoting activity. Displays

a preference for an acidic residue N-terminal to the isomerized proline

bond. Catalyzing pSer/Thr-Pro cis/trans isomerizations.

PIN1 Sequence databases

EMBL

DDBJ

GenBank

PIN1 3D structure databases

ModBase

PIN1 Protein-protein interaction databases

STRING

PIN1 Proteomic databases

PRIDE

PIN1 Genome annotation databases

Ensembl

GeneID

KEGG

UCSC

PIN1 Organism specific databases

CTD

MGI

PIN1 Phylogenomic databases

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

PIN1 Gene expression databases

Bgee

ArrayExpress

Genevestigator

PIN1 Family and domain databases

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY