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Human Tumor necrosis factor receptor superfamily member 1A (a.a.22–211)

TNFRSF1A Swiss Prot#

P19438

TNFRSF1A Protein names

Tumor necrosis factor receptor superfamily member 1A (Tumor necrosis

factor receptor 1) (TNF-R1) (Tumor necrosis factor receptor type I) (TNF-RI)

(TNFR-I) (p60) (p55) (CD antigen CD120a) [Cleaved into: Tumor necrosis

factor receptor superfamily member 1A,

TNFRSF1A Gene names

TNFRSF1A (TNFAR) (TNFR1)

Organism

Human

TNFRSF1A Entry name

NFKB2_HUMAN

TNFRSF1A Codon optimized cDNA Clone

TNFRSF1A CDNA Cat#

RPE0734

cDNA Tag

cDNA TNFRSF1A Contains A 6x histidine tag

Condon optimized TNFRSF1A CDNA Formulation

Liquid

Condon optimized TNFRSF1A CDNA Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

Condon optimized TNFRSF1A cDNA Applications

Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant TNFRSF1A Protein

Recombinant TNFRSF1A Protein Cat#

PE0734

TNFRSF1A Protein Source

Recombinant protein.

Recombinant TNFRSF1A Protein Applications

Western Blot, may be used for other applications determined by user

Recombinant TNFRSF1A Protein Purity

>90%, as determined by SDS-PAGE under reducing conditions

Recombinant TNFRSF1A Protein Activity

N/A

Recombinant protein Tag

Recombinant TNFRSF1A contains A 6x histidine tag

Recombinant TNFRSF1A Protein Formulation

Liquid

Recombinant TNFRSF1A Protein Storage

Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

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TNFRSF1A Protein family

TNFRSF1A Subcellular locations

Cell membrane; Single-pass type I membrane protein. Secreted.

TNFRSF1A FUNCTION (According to UniProtKB/Swiss Prot)

FUNCTION: Receptor for TNFSF2/TNF-alpha and homotrimeric

TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8

to the activated receptor. The resulting death-inducing signaling complex

(DISC) performs caspase-8 proteolytic activation which initiates the

subsequent cascade of caspases (aspartate-specific cysteine proteases)

mediating apoptosis. Contributes to the induction of non-cytocidal TNF

effects including anti-viral state and activation of the acid

sphingomyelinase.

TNFRSF1A Sequence databases

EMBL

DDBJ

GenBank

TNFRSF1A 3D structure databases

ModBase

TNFRSF1A Protein-protein interaction databases

STRING

TNFRSF1A Proteomic databases

PRIDE

TNFRSF1A Genome annotation databases

Ensembl

GeneID

KEGG

UCSC

TNFRSF1A Organism specific databases

CTD

MGI

TNFRSF1A Phylogenomic databases

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

TNFRSF1A Gene expression databases

Bgee

ArrayExpress

Genevestigator

TNFRSF1A Family and domain databases

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY