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Human Tumor necrosis factor receptor superfamily member 1B (a.a.23–257)

TNFRSF1B Swiss Prot#

P20333

TNFRSF1B Protein names

Tumor necrosis factor receptor superfamily member 1B (Tumor necrosis

factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (TNF-RII)

(TNFR-II) (p75) (p80 TNF-alpha receptor) (CD antigen CD120b) (Etanercept)

[Cleaved into: Tumor necrosis fac

TNFRSF1B Gene names

TNFRSF1B (TNFBR) (TNFR2)

Organism

Human

TNFRSF1B Entry name

ACM1_HUMAN

TNFRSF1B Codon optimized cDNA Clone

TNFRSF1B CDNA Cat#

RPE0739

cDNA Tag

cDNA TNFRSF1B Contains A 6x histidine tag

Condon optimized TNFRSF1B CDNA Formulation

Liquid

Condon optimized TNFRSF1B CDNA Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

Condon optimized TNFRSF1B cDNA Applications

Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant TNFRSF1B Protein

Recombinant TNFRSF1B Protein Cat#

PE0739

TNFRSF1B Protein Source

Recombinant protein.

Recombinant TNFRSF1B Protein Applications

Western Blot, may be used for other applications determined by user

Recombinant TNFRSF1B Protein Purity

>90%, as determined by SDS-PAGE under reducing conditions

Recombinant TNFRSF1B Protein Activity

N/A

Recombinant protein Tag

Recombinant TNFRSF1B contains A 6x histidine tag

Recombinant TNFRSF1B Protein Formulation

Liquid

Recombinant TNFRSF1B Protein Storage

Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

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TNFRSF1B Protein family

TNFRSF1B Subcellular locations

Cell membrane; Single-pass type I membrane protein. Secreted.

TNFRSF1B FUNCTION (According to UniProtKB/Swiss Prot)

FUNCTION: Receptor with high affinity for TNFSF2/TNF-alpha and

approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-

alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2

and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the

metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced

apoptosis, which suggests that it regulates TNF-alpha function by

antagonizing its biological activity.

TNFRSF1B Sequence databases

EMBL

DDBJ

GenBank

TNFRSF1B 3D structure databases

ModBase

TNFRSF1B Protein-protein interaction databases

STRING

TNFRSF1B Proteomic databases

PRIDE

TNFRSF1B Genome annotation databases

Ensembl

GeneID

KEGG

UCSC

TNFRSF1B Organism specific databases

CTD

MGI

TNFRSF1B Phylogenomic databases

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

TNFRSF1B Gene expression databases

Bgee

ArrayExpress

Genevestigator

TNFRSF1B Family and domain databases

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY