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Human Thioredoxin (a.a.2–105)

TXN Swiss Prot#

P10599

TXN Protein names

Thioredoxin (Trx) (ATL-derived factor) (ADF) (Surface-associated sulphydryl

protein) (SASP)

TXN Gene names

TXN (TRDX) (TRX) (TRX1)

Organism

Human

TXN Entry name

THIO_HUMAN

TXN Codon optimized cDNA Clone

TXN CDNA Cat#

RPE0410

cDNA Tag

cDNA TXN Contains A 6x histidine tag

Condon optimized TXN CDNA Formulation

Liquid

Condon optimized TXN CDNA Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

Condon optimized TXN cDNA Applications

Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant TXN Protein

Recombinant TXN Protein Cat#

PE0410

TXN Protein Source

Recombinant protein.

Recombinant TXN Protein Applications

Western Blot, may be used for other applications determined by user

Recombinant TXN Protein Purity

>90%, as determined by SDS-PAGE under reducing conditions

Recombinant TXN Protein Activity

N/A

Recombinant protein Tag

Recombinant TXN contains A 6x histidine tag

Recombinant TXN Protein Formulation

Liquid

Recombinant TXN Protein Storage

Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

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TXN Protein family

Thioredoxin family

TXN Subcellular locations

Nucleus. Cytoplasm. Secreted.

TXN FUNCTION (According to UniProtKB/Swiss Prot)

FUNCTION: Participates in various redox reactions through the reversible

oxidation of its active center dithiol to a disulfide and catalyzes dithiol-

disulfide exchange reactions. Plays a role in the reversible S-nitrosylation

of cysteine residues in target proteins, and thereby contributes to the

response to intracellular nitric oxide. Nitrosylates the active site Cys of

CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3

activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing

radiation (IR) cells through its oxidation/reduction status and stimulates AP-

1 transcriptional activity.; FUNCTION: ADF augments the expression of the

interleukin-2 receptor TAC (IL2R/P55).

TXN Sequence databases

EMBL

DDBJ

GenBank

TXN 3D structure databases

ModBase

TXN Protein-protein interaction databases

STRING

TXN Proteomic databases

PRIDE

TXN Genome annotation databases

Ensembl

GeneID

KEGG

UCSC

TXN Organism specific databases

CTD

MGI

TXN Phylogenomic databases

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

TXN Gene expression databases

Bgee

ArrayExpress

Genevestigator

TXN Family and domain databases

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY