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Human Pyruvate carboxylase, mitochondrial (a.a.36–486)
PC Swiss Prot#
P11498
PC Protein names
Pyruvate carboxylase, mitochondrial (EC 6.4.1.1) (Pyruvic carboxylase)

(PCB)
PC Gene names
PC
Organism
Human
PC Entry name
ADA2A_HUMAN
PC Codon optimized cDNA Clone
PC CDNA Cat#
RPE0730
cDNA Tag
cDNA PC Contains A 6x histidine tag
Condon optimized PC CDNA Formulation
Liquid
Condon optimized PC CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized PC cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant PC Protein
Recombinant PC Protein Cat#
PE0730
PC Protein Source
Recombinant protein.
Recombinant PC Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant PC Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant PC Protein Activity
N/A
Recombinant protein Tag
Recombinant PC contains A 6x histidine tag
Recombinant PC Protein Formulation
Liquid
Recombinant PC Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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PC Protein family
-
PC Subcellular locations
Mitochondrion matrix.
PC FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Pyruvate carboxylase catalyzes a 2-step reaction, involving the

ATP-dependent carboxylation of the covalently attached biotin in the first

step and the transfer of the carboxyl group to pyruvate in the second.

Catalyzes in a tissue specific manner, the initial reactions of glucose (liver,

kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate.
PC Sequence databases
EMBL DDBJ GenBank
PC 3D structure databases
ModBase
PC Protein-protein interaction databases
STRING
PC Proteomic databases
PRIDE
PC Genome annotation databases
Ensembl GeneID KEGG UCSC
PC Organism specific databases
CTD MGI
PC Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
PC Gene expression databases
Bgee ArrayExpress Genevestigator
PC Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY