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Magnetic Separator
Magnetic Beads and Applications
Affinity Magnetic Beads
  • Amine-terminated
  • Aldehyde-
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Reversed-Phase  Beads
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  • Cyanopropyl
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Ion Exchange Beads
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Antibody Purification & IP
  • Protein A
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Antibody Immobilization
  • Protein A
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  • Protein L
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Recombinant Protein
Purification
  • Ni+ Charged Beads
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Peptide Immobilization
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Carbohydrate
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Abundant Protein Removal
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EDTA-Magnetic BEads
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Human Breast cancer type 2 susceptibility protein (a.a.2350–2545)
BRCA2 Swiss Prot#
P51587
BRCA2 Protein names
Breast cancer type 2 susceptibility protein (Fanconi anemia group D1

protein)
BRCA2 Gene names
BRCA2 (FACD) (FANCD1)
Organism
Human
BRCA2 Entry name
BRCA2_HUMAN
BRCA2 Codon optimized cDNA Clone
BRCA2 CDNA Cat#
RPE0458
cDNA Tag
cDNA BRCA2 Contains A 6x histidine tag
Condon optimized BRCA2 CDNA Formulation
Liquid
Condon optimized BRCA2 CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized BRCA2 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant BRCA2 Protein

Recombinant BRCA2 Protein Cat#
PE0458
BRCA2 Protein Source
Recombinant protein.
Recombinant BRCA2 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant BRCA2 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant BRCA2 Protein Activity
N/A
Recombinant protein Tag
Recombinant BRCA2 contains A 6x histidine tag
Recombinant BRCA2 Protein Formulation
Liquid
Recombinant BRCA2 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Place Order for Recombinant BRCA2 Protein or cDNA
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BRCA2 Protein family
-
BRCA2 Subcellular locations
-
BRCA2 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Involved in double-strand break repair and/or homologous

recombination. Binds RAD51 and potentiates recombinational DNA repair by

promoting assembly of RAD51 onto single-stranded DNA (ssDNA). Acts by

targeting RAD51 to ssDNA over double-stranded DNA, enabling RAD51 to

displace replication protein-A (RPA) from ssDNA and stabilizing RAD51-

ssDNA filaments by blocking ATP hydrolysis. May participate in S phase

checkpoint activation. Binds selectively to ssDNA, and to ssDNA in tailed

duplexes and replication fork structures.
BRCA2 Sequence databases
EMBL DDBJ GenBank
BRCA2 3D structure databases
ModBase
BRCA2 Protein-protein interaction databases
STRING
BRCA2 Proteomic databases
PRIDE
BRCA2 Genome annotation databases
Ensembl GeneID KEGG UCSC
BRCA2 Organism specific databases
CTD MGI
BRCA2 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
BRCA2 Gene expression databases
Bgee ArrayExpress Genevestigator
BRCA2 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY