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Human TSG101 (a.a.1-390)

TSG101 Swiss Prot#

Q99816

TSG101 Protein names

Tumor susceptibility gene 101 protein (ESCRT-I complex subunit TSG101)

TSG101 Gene names

TSG101

Organism

Human

TSG101 Entry name

TS101_HUMAN

TSG101 Codon optimized cDNA Clone

TSG101 CDNA Cat#

RPE0162

cDNA Tag

cDNA TSG101 Contains A 6x histidine tag

Condon optimized TSG101 CDNA Formulation

Liquid

Condon optimized TSG101 CDNA Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

Condon optimized TSG101 cDNA Applications

Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant TSG101 Protein

Recombinant TSG101 Protein Cat#

PE0162

TSG101 Protein Source

Recombinant protein.

Recombinant TSG101 Protein Applications

Western Blot, may be used for other applications determined by user

Recombinant TSG101 Protein Purity

>90%, as determined by SDS-PAGE under reducing conditions

Recombinant TSG101 Protein Activity

N/A

Recombinant protein Tag

Recombinant TSG101 contains A 6x histidine tag

Recombinant TSG101 Protein Formulation

Liquid

Recombinant TSG101 Protein Storage

Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

Place Order for Recombinant TSG101 Protein or cDNA

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TSG101 Protein family

Ubiquitin-conjugating enzyme family, UEV subfamily

TSG101 Subcellular locations

Cytoplasm. Membrane; Peripheral membrane protein. Nucleus. Late

endosome membrane; Peripheral membrane protein.

TSG101 FUNCTION (According to UniProtKB/Swiss Prot)

FUNCTION: Component of the ESCRT-I complex, a regulator of vesicular

trafficking process. Binds to ubiquitinated cargo proteins and is required for

the sorting of endocytic ubiquitinated cargos into multivesicular bodies

(MVBs). Mediates the association between the ESCRT-0 and ESCRT-I

complex. Required for completion of cytokinesis; the function requires

CEP55. May be involved in cell growth and differentiation. Acts as a

negative growth regulator. Involved in the budding of many viruses through

an interaction with viral proteins that contain a late-budding motif P-[ST]-A-

P. This interaction is essential for viral particle budding of numerous

retroviruses.

TSG101 Sequence databases

EMBL

DDBJ

GenBank

TSG101 3D structure databases

ModBase

TSG101 Protein-protein interaction databases

STRING

TSG101 Proteomic databases

PRIDE

TSG101 Genome annotation databases

Ensembl

GeneID

KEGG

UCSC

TSG101 Organism specific databases

CTD

MGI

TSG101 Phylogenomic databases

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

TSG101 Gene expression databases

Bgee

ArrayExpress

Genevestigator

TSG101 Family and domain databases

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY