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Human YBX1 (NSEP1) (YB1) (a.a. 2-324)
YBX1 Swiss Prot#
P67809
YBX1 Protein names
Nuclease-sensitive element-binding protein 1 (Y-box-binding protein 1) (Y-

box transcription factor) (YB-1) (CCAAT-binding transcription factor I subunit

A) (CBF-A) (Enhancer factor I subunit A) (EFI-A) (DNA-binding protein B)

(DBPB)
YBX1 Gene names
YBX1 (NSEP1) (YB1)
Organism
Human
YBX1 Entry name
YBOX1_HUMAN
YBX1 Codon optimized cDNA Clone
YBX1 CDNA Cat#
RPE0110
cDNA Tag
cDNA YBX1 Contains A 6x histidine tag
Condon optimized YBX1 CDNA Formulation
Liquid
Condon optimized YBX1 CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized YBX1 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant YBX1 Protein
Recombinant YBX1 Protein Cat#
PE0110
YBX1 Protein Source
Recombinant protein.
Recombinant YBX1 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant YBX1 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant YBX1 Protein Activity
N/A
Recombinant protein Tag
Recombinant YBX1 contains A 6x histidine tag
Recombinant YBX1 Protein Formulation
Liquid
Recombinant YBX1 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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YBX1 Protein family
-
YBX1 Subcellular locations
Cytoplasm. Nucleus. Cytoplasmic granule. Secreted.
YBX1 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Mediates pre-mRNA alternative splicing regulation. Binds to

splice sites in pre-mRNA and regulates splice site selection. Binds and

stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by

modulating the interaction between the mRNA and eukaryotic initiation

factors (By similarity). Regulates the transcription of numerous genes. Its

transcriptional activity on the multidrug resistance gene MDR1 is enhanced

in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds to

promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as MDR1 and

HLA class II genes. Promotes separation of DNA strands that contain

mismatches or are modified by cisplatin. Has endonucleolytic activity and

can introduce nicks or breaks into double-stranded DNA (in vitro). May play

a role in DNA repair. Component of the CRD-mediated complex that

promotes MYC mRNA stability.; FUNCTION: The secreted form acts as an

extracellular mitogen and stimulates cell migration and proliferation.
YBX1 Sequence databases
EMBL DDBJ GenBank
YBX1 3D structure databases
ModBase
YBX1 Protein-protein interaction databases
STRING
YBX1 Proteomic databases
PRIDE
YBX1 Genome annotation databases
Ensembl GeneID KEGG UCSC
YBX1 Organism specific databases
CTD MGI
YBX1 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
YBX1 Gene expression databases
Bgee ArrayExpress Genevestigator
YBX1 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY