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Affinity Magnetic Beads
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Human HBEGF (DTR) (DTS) (HEGFL) (a.a. 21- 208)
HBEGF Swiss Prot#
Q99075
HBEGF Protein names
Proheparin-binding EGF-like growth factor [Cleaved into: Heparin-binding

EGF-like growth factor (HB-EGF) (HBEGF) (Diphtheria toxin receptor) (DT-R)]
HBEGF Gene names
HBEGF (DTR) (DTS) (HEGFL)
Organism
Human
HBEGF Entry name
HBEGF_HUMAN
HBEGF Codon optimized cDNA Clone
HBEGF CDNA Cat#
RPE0047
cDNA Tag
cDNA HBEGF Contains A 6x histidine tag
Condon optimized HBEGF CDNA Formulation
Liquid
Condon optimized HBEGF CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized HBEGF cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant HBEGF Protein
Recombinant HBEGF Protein Cat#
PE0047
HBEGF Protein Source
Recombinant protein.
Recombinant HBEGF Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant HBEGF Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant HBEGF Protein Activity
N/A
Recombinant protein Tag
Recombinant HBEGF contains A 6x histidine tag
Recombinant HBEGF Protein Formulation
Liquid
Recombinant HBEGF Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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HBEGF Protein family
-
HBEGF Subcellular locations
Secreted > extracellular space. Cell membrane; Single-pass type I

membrane protein.
HBEGF FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: May be involved in macrophage-mediated cellular proliferation.

It is mitogenic for fibroblasts and smooth muscle but not endothelial cells. It

is able to bind EGF receptors with higher affinity than EGF itself and is a far

more potent mitogen for smooth muscle cells than EGF. Also acts as a

diphtheria toxin receptor.
HBEGF Sequence databases
EMBL DDBJ GenBank
HBEGF 3D structure databases
ModBase
HBEGF Protein-protein interaction databases
STRING
HBEGF Proteomic databases
PRIDE
HBEGF Genome annotation databases
Ensembl GeneID KEGG UCSC
HBEGF Organism specific databases
CTD MGI
HBEGF Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
HBEGF Gene expression databases
Bgee ArrayExpress Genevestigator
HBEGF Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY