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Bio-Magnetic Purification
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Magnetic Separator
Magnetic Beads and Applications
Affinity Magnetic Beads
  • Amine-terminated
  • Aldehyde-
  • Carboxyl-terminated
  • CDI-activated
  • DVS
  • DADPA-terminated
  • Epoxy
  • Hydrazide-terminated
  • Hydroxyl-terminated
  • Iodoacetyl
  • NHS
  • Sulfhydryl-terminated
  • Tosyl
  • Thiol
  • Silica
  • IDA-modified
Reversed-Phase  Beads
  • C4
  • C8
  • C18
  • Cyanopropyl
  • Phenyl
  • diPhenyl
Ion Exchange Beads
  • DEAE (WAX)
  • PSA (WAX)
  • SAX
  • WCX
  • SCX
  • Hydroxyapatite
Antibody Purification & IP
  • Protein A
  • Protein G
  • Protein A/G
  • Protein L
  • Quick IgG Pure Beads
  • Antigen Peptide
  • Quick IgM Pure Beads
  • Anti-IgG Beads
  • Quick IgA Pure Bead
  • Thiophillic Beads
Antibody Immobilization
  • Protein A
  • Protein G
  • Protein A/G
  • Protein L
  • Epoxy
  • Aldehyde-
  • Hydrazide-terminated
  • Carboxyl-terminated
  • Iodoacetyl
  • Thiol
Recombinant Protein
Purification
  • Ni+ Charged Beads
  • Co+ Charged Beads
  • Maltose
  • Calmodulin Beads
Peptide Immobilization
  • Epoxy
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  • Carboxyl-terminated
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  • Iodoacetyl
  • Thiol
DNA/RNA Purification
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    (Mutation Isolation)
DNA/RNA Immobilization
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Endotoxin Removal
Small Molecule
Immobilization
Carbohydrate
Immobilization
  • Epoxy
  • Aldehyde-
  • Hydrazide-terminated
  • DVS
Abundant Protein Removal
  • HSA Removal
  • IgG Removal
  • HSA/IgG Removal
  • Abundant-10 Protein
  • Abundant-22 Protein
 
Cell Isolation
  • Virus
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  • Cell
  • Parasites
EDTA-Magnetic BEads
Miscellaneous
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IDA-Magnetic Beads
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  • For cDNA or Recombinant Protein Search ( Input Cat#,
    or Gene name, or Protein Name, or Accession Number
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Human PRNP (PRIP) (PRP) (a.a. 23-230)
PRNP Swiss Prot#
P04156
PRNP Protein names
Major prion protein (PrP) (PrP27-30) (PrP33-35C) (ASCR) (CD antigen

CD230)
PRNP Gene names
PRNP (PRIP) (PRP)
Organism
Human
PRNP Entry name
PRIO_HUMAN
PRNP Codon optimized cDNA Clone
PRNP CDNA Cat#
RPE0072
cDNA Tag
cDNA PRNP Contains A 6x histidine tag
Condon optimized PRNP CDNA Formulation
Liquid
Condon optimized PRNP CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized PRNP cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant PRNP Protein
Recombinant PRNP Protein Cat#
PE0072
PRNP Protein Source
Recombinant protein.
Recombinant PRNP Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant PRNP Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant PRNP Protein Activity
N/A
Recombinant protein Tag
Recombinant PRNP contains A 6x histidine tag
Recombinant PRNP Protein Formulation
Liquid
Recombinant PRNP Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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PRNP Protein family
Prion family
PRNP Subcellular locations
Cell membrane; Lipid-anchor > GPI-anchor. Golgi apparatus. Cytoplasm.

Nucleus.
PRNP FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: The function of PrP is still under debate. May play a role in

neuronal development and synaptic plasticity. May be required for neuronal

myelin sheath maintenance. May play a role in iron uptake and iron

homeostasis (By similarity). Isoform 2 may act as a growth suppressor by

arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to

cultured neuroblastoma cells and induce apoptosis (in vitro).
PRNP Sequence databases
EMBL DDBJ GenBank
PRNP 3D structure databases
ModBase
PRNP Protein-protein interaction databases
STRING
PRNP Proteomic databases
PRIDE
PRNP Genome annotation databases
Ensembl GeneID KEGG UCSC
PRNP Organism specific databases
CTD MGI
PRNP Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
PRNP Gene expression databases
Bgee ArrayExpress Genevestigator
PRNP Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY