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Human RBBP4 (RBAP48) (a.a. 2-425)

RBBP4 Swiss Prot#

Q09028

RBBP4 Protein names

Histone-binding protein RBBP4 (Retinoblastoma-binding protein 4) (RBBP-4)

(Retinoblastoma-binding protein p48) (Chromatin assembly factor 1 subunit

C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48

kDa subunit) (CAF-I p48) (Nucleoso

RBBP4 Gene names

RBBP4 (RBAP48)

Organism

Human

RBBP4 Entry name

RBBP4_HUMAN

RBBP4 Codon optimized cDNA Clone

RBBP4 CDNA Cat#

RPE0188

cDNA Tag

cDNA RBBP4 Contains A 6x histidine tag

Condon optimized RBBP4 CDNA Formulation

Liquid

Condon optimized RBBP4 CDNA Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

Condon optimized RBBP4 cDNA Applications

Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant RBBP4 Protein

Recombinant RBBP4 Protein Cat#

PE0188

RBBP4 Protein Source

Recombinant protein.

Recombinant RBBP4 Protein Applications

Western Blot, may be used for other applications determined by user

Recombinant RBBP4 Protein Purity

>90%, as determined by SDS-PAGE under reducing conditions

Recombinant RBBP4 Protein Activity

N/A

Recombinant protein Tag

Recombinant RBBP4 contains A 6x histidine tag

Recombinant RBBP4 Protein Formulation

Liquid

Recombinant RBBP4 Protein Storage

Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

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RBBP4 Protein family

WD repeat RBAP46/RBAP48/MSI1 family

RBBP4 Subcellular locations

Nucleus.

RBBP4 FUNCTION (According to UniProtKB/Swiss Prot)

FUNCTION: Core histone-binding subunit that may target chromatin

assembly factors, chromatin remodeling factors and histone deacetylases to

their histone substrates in a manner that is regulated by nucleosomal DNA.

Component of several complexes which regulate chromatin metabolism.

These include the chromatin assembly factor 1 (CAF-1) complex, which is

required for chromatin assembly following DNA replication and DNA repair;

the core histone deacetylase (HDAC) complex, which promotes histone

deacetylation and consequent transcriptional repression; the nucleosome

remodeling and histone deacetylase complex (the NuRD complex), which

promotes transcriptional repression by histone deacetylation and

nucleosome remodeling; the PRC2/EED-EZH2 complex, which promotes

repression of homeotic genes during development; and the NURF

(nucleosome remodeling factor) complex.

RBBP4 Sequence databases

EMBL

DDBJ

GenBank

RBBP4 3D structure databases

ModBase

RBBP4 Protein-protein interaction databases

STRING

RBBP4 Proteomic databases

PRIDE

RBBP4 Genome annotation databases

Ensembl

GeneID

KEGG

UCSC

RBBP4 Organism specific databases

CTD

MGI

RBBP4 Phylogenomic databases

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

RBBP4 Gene expression databases

Bgee

ArrayExpress

Genevestigator

RBBP4 Family and domain databases

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY